Abstract
This study was designed to determine whether axons of cholinergic dorsal tegmental neurons terminate on cells in the anterior thalamus in rabbits as in other species, and to localize projecting tegmental cells for future studies of their contributions to anterior thalamic learning-relevant neuronal activity. The distribution of retrogradely labeled neurons was examined following injections of wheat germ agglutinin horseradish peroxidase (WGA-HRP) centered in the anterior ventral (AV) thalamic nucleus. The results confirm past findings in rabbits indicating projections to anterior thalamus from the mammillary nuclei, the posterior cingulate cortex, presubiculum and postsubiculum. Demonstrated for the first time in rabbits were projections from the lateral dorsal and the pedunculopontine tegmental nuclei, locus coeruleus, dorsal raphe nucleus, Gudden's dorsal tegmental nucleus, pretectum and reticular thalamic nucleus.
Publication types
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Research Support, U.S. Gov't, Non-P.H.S.
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Afferent Pathways / anatomy & histology
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Afferent Pathways / cytology
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Afferent Pathways / physiology
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Animals
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Axons / physiology
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Brain Stem / anatomy & histology
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Brain Stem / cytology
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Brain Stem / physiology
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Cerebral Cortex / anatomy & histology
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Cerebral Cortex / cytology
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Cerebral Cortex / physiology
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Diencephalon / anatomy & histology
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Diencephalon / cytology
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Diencephalon / physiology
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Histocytochemistry
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Horseradish Peroxidase
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Male
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Neurons, Afferent / physiology*
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Rabbits
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Tegmentum Mesencephali / anatomy & histology
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Tegmentum Mesencephali / cytology
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Tegmentum Mesencephali / physiology
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Thalamus / anatomy & histology*
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Thalamus / cytology
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Thalamus / physiology
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Wheat Germ Agglutinin-Horseradish Peroxidase Conjugate
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Wheat Germ Agglutinins
Substances
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Wheat Germ Agglutinin-Horseradish Peroxidase Conjugate
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Wheat Germ Agglutinins
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Horseradish Peroxidase