Advances in our understanding of the mechanisms of the neurotoxicity of MPTP and related compounds

J Neurochem. 1993 Oct;61(4):1191-206. doi: 10.1111/j.1471-4159.1993.tb13610.x.
No abstract available

Publication types

  • Review

MeSH terms

  • 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine / metabolism
  • 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine / pharmacology*
  • 1-Methyl-4-phenylpyridinium / pharmacokinetics
  • 1-Methyl-4-phenylpyridinium / pharmacology*
  • Aging / physiology
  • Animals
  • Biological Transport
  • Humans
  • Mitochondria / drug effects
  • Mitochondria / physiology
  • Nervous System / drug effects*
  • Oxidation-Reduction
  • Parkinson Disease / physiopathology
  • Selegiline / pharmacology
  • Species Specificity

Substances

  • Selegiline
  • 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine
  • 1-Methyl-4-phenylpyridinium