APC gene: database of germline and somatic mutations in human tumors and cell lines

C Béroud; T Soussi

doi:10.1093/nar/24.1.121

APC gene: database of germline and somatic mutations in human tumors and cell lines

Nucleic Acids Res. 1996 Jan 1;24(1):121-4. doi: 10.1093/nar/24.1.121.

Authors

C Béroud¹, T Soussi

Affiliation

¹ Hôpital Necker Enfants Malades, U383 INSERM, Paris, France.

Abstract

A database is described in which over 700 mutations in the human APC gene of tumors (colon cancer predominantly) are compiled from the literature. It includes both molecular informations about the mutations and also clinical data about the patients. A software have been designed in order to analyse all these informations in the database.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Adenomatous Polyposis Coli / genetics
Cell Line
Colorectal Neoplasms / genetics*
DNA Mutational Analysis
Databases, Factual*
Female
Genes, APC*
Germ-Line Mutation*
Humans
Ovarian Neoplasms / genetics
Pancreatic Neoplasms / genetics
Stomach Neoplasms / genetics
Thyroid Neoplasms / genetics