Abstract
The putative membrane fatty acid transporter (FAT) protein and its mRNA, originally expressed in adipose tissue, were found in the tongue of rats. Northern blot analysis showed a significant expression of FAT mRNA in the epithelial layer of circumvallate papillae. Immunohistochemical staining revealed that immunoreactivity for FAT is specifically localized in the apical part of taste bud cells, possibly gustatory cells, in the circumvallate papillae.
MeSH terms
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Animals
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Base Sequence
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CD36 Antigens / chemistry
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CD36 Antigens / genetics
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Carrier Proteins / biosynthesis*
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Carrier Proteins / genetics
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Conserved Sequence
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DNA Primers
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Epithelial Cells
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Epithelium / metabolism
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Fatty Acid-Binding Protein 7
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Fatty Acid-Binding Proteins
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Fatty Acids / metabolism
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Humans
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Immunohistochemistry
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Molecular Sequence Data
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Multigene Family
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Myelin P2 Protein / biosynthesis*
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Myelin P2 Protein / genetics
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Neoplasm Proteins*
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Nerve Tissue Proteins*
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Polymerase Chain Reaction
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RNA, Messenger / biosynthesis
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Rats
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Sequence Alignment
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Sequence Homology, Nucleic Acid
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Taste Buds / cytology
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Taste Buds / metabolism*
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Transcription, Genetic*
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Tumor Suppressor Proteins*
Substances
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CD36 Antigens
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Carrier Proteins
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DNA Primers
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FABP7 protein, human
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Fabp7 protein, rat
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Fatty Acid-Binding Protein 7
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Fatty Acid-Binding Proteins
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Fatty Acids
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Myelin P2 Protein
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Neoplasm Proteins
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Nerve Tissue Proteins
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RNA, Messenger
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Tumor Suppressor Proteins