The role of interleukin 1 in acute neurodegeneration and stroke: pathophysiological and therapeutic implications

J Clin Invest. 1997 Dec 1;100(11):2648-52. doi: 10.1172/JCI119808.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Acute Disease
  • Animals
  • Apoptosis
  • Brain / immunology
  • Caspase 1
  • Cerebrovascular Disorders / immunology*
  • Cerebrovascular Disorders / therapy
  • Cysteine Endopeptidases / metabolism
  • Humans
  • Interleukin 1 Receptor Antagonist Protein
  • Interleukin-1 / antagonists & inhibitors
  • Interleukin-1 / immunology*
  • Neurodegenerative Diseases / immunology*
  • Neurodegenerative Diseases / therapy
  • Neurons / cytology
  • Sialoglycoproteins / therapeutic use

Substances

  • IL1RN protein, human
  • Interleukin 1 Receptor Antagonist Protein
  • Interleukin-1
  • Sialoglycoproteins
  • Cysteine Endopeptidases
  • Caspase 1