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Specific role of VTA dopamine neuronal firing rates and morphology in the reversal of anxiety-related, but not depression-related behavior in the ClockΔ19 mouse model of mania.
Coque L, Mukherjee S, Cao JL, Spencer S, Marvin M, Falcon E, Sidor MM, Birnbaum SG, Graham A, Neve RL, Gordon E, Ozburn AR, Goldberg MS, Han MH, Cooper DC, McClung CA. Coque L, et al. Neuropsychopharmacology. 2011 Jun;36(7):1478-88. doi: 10.1038/npp.2011.33. Epub 2011 Mar 23. Neuropsychopharmacology. 2011. PMID: 21430648 Free PMC article.
Knockdown of Clock in the ventral tegmental area through RNA interference results in a mixed state of mania and depression-like behavior.
Mukherjee S, Coque L, Cao JL, Kumar J, Chakravarty S, Asaithamby A, Graham A, Gordon E, Enwright JF 3rd, DiLeone RJ, Birnbaum SG, Cooper DC, McClung CA. Mukherjee S, et al. Among authors: coque l. Biol Psychiatry. 2010 Sep 15;68(6):503-11. doi: 10.1016/j.biopsych.2010.04.031. Epub 2010 Jun 29. Biol Psychiatry. 2010. PMID: 20591414 Free PMC article.