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Locus ceruleus controls Alzheimer's disease pathology by modulating microglial functions through norepinephrine.
Heneka MT, Nadrigny F, Regen T, Martinez-Hernandez A, Dumitrescu-Ozimek L, Terwel D, Jardanhazi-Kurutz D, Walter J, Kirchhoff F, Hanisch UK, Kummer MP. Heneka MT, et al. Among authors: dumitrescu ozimek l. Proc Natl Acad Sci U S A. 2010 Mar 30;107(13):6058-63. doi: 10.1073/pnas.0909586107. Epub 2010 Mar 15. Proc Natl Acad Sci U S A. 2010. PMID: 20231476 Free PMC article.
Nonsteroidal anti-inflammatory drugs repress beta-secretase gene promoter activity by the activation of PPARgamma.
Sastre M, Dewachter I, Rossner S, Bogdanovic N, Rosen E, Borghgraef P, Evert BO, Dumitrescu-Ozimek L, Thal DR, Landreth G, Walter J, Klockgether T, van Leuven F, Heneka MT. Sastre M, et al. Among authors: dumitrescu ozimek l. Proc Natl Acad Sci U S A. 2006 Jan 10;103(2):443-8. doi: 10.1073/pnas.0503839103. Epub 2006 Jan 3. Proc Natl Acad Sci U S A. 2006. PMID: 16407166 Free PMC article.