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Some taste substances are direct activators of G-proteins.
Naim M, Seifert R, Nürnberg B, Grünbaum L, Schultz G. Naim M, et al. Among authors: grunbaum l. Biochem J. 1994 Feb 1;297 ( Pt 3)(Pt 3):451-4. doi: 10.1042/bj2970451. Biochem J. 1994. PMID: 8110180 Free PMC article.
Histamine receptor-dependent and/or -independent activation of guanine nucleotide-binding proteins by histamine and 2-substituted histamine derivatives in human leukemia (HL-60) and human erythroleukemia (HEL) cells.
Hagelüken A, Grünbaum L, Klinker JF, Nürnberg B, Harhammer R, Schultz G, Leschke C, Schunack W, Seifert R. Hagelüken A, et al. Among authors: grunbaum l. Biochem Pharmacol. 1995 Mar 30;49(7):901-914. doi: 10.1016/0006-2952(94)00514-m. Biochem Pharmacol. 1995. PMID: 7741762
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