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Overexpression of the steroidogenic enzyme cytochrome P450 side chain cleavage in the ventral tegmental area increases 3α,5α-THP and reduces long-term operant ethanol self-administration.
Cook JB, Werner DF, Maldonado-Devincci AM, Leonard MN, Fisher KR, O'Buckley TK, Porcu P, McCown TJ, Besheer J, Hodge CW, Morrow AL. Cook JB, et al. Among authors: leonard mn. J Neurosci. 2014 Apr 23;34(17):5824-34. doi: 10.1523/JNEUROSCI.4733-13.2014. J Neurosci. 2014. PMID: 24760842 Free PMC article.