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Page 1
Rescue of neuropsychiatric phenotypes in a mouse model of 16p11.2 duplication syndrome by genetic correction of an epilepsy network hub.
Forrest MP, Dos Santos M, Piguel NH, Wang YZ, Hawkins NA, Bagchi VA, Dionisio LE, Yoon S, Simkin D, Martin-de-Saavedra MD, Gao R, Horan KE, George AL Jr, LeDoux MS, Kearney JA, Savas JN, Penzes P. Forrest MP, et al. Among authors: piguel nh. Nat Commun. 2023 Feb 17;14(1):825. doi: 10.1038/s41467-023-36087-x. Nat Commun. 2023. PMID: 36808153 Free PMC article.
Multiple genes in a single GWAS risk locus synergistically mediate aberrant synaptic development and function in human neurons.
Zhang S, Zhang H, Forrest MP, Zhou Y, Sun X, Bagchi VA, Kozlova A, Santos MD, Piguel NH, Dionisio LE, Sanders AR, Pang ZP, He X, Penzes P, Duan J. Zhang S, et al. Among authors: piguel nh. Cell Genom. 2023 Aug 28;3(9):100399. doi: 10.1016/j.xgen.2023.100399. eCollection 2023 Sep 13. Cell Genom. 2023. PMID: 37719141 Free PMC article.
Excitatory Dysfunction Drives Network and Calcium Handling Deficits in 16p11.2 Duplication Schizophrenia Induced Pluripotent Stem Cell-Derived Neurons.
Parnell E, Culotta L, Forrest MP, Jalloul HA, Eckman BL, Loizzo DD, Horan KKE, Dos Santos M, Piguel NH, Tai DJC, Zhang H, Gertler TS, Simkin D, Sanders AR, Talkowski ME, Gejman PV, Kiskinis E, Duan J, Penzes P. Parnell E, et al. Among authors: piguel nh. Biol Psychiatry. 2023 Jul 15;94(2):153-163. doi: 10.1016/j.biopsych.2022.11.005. Epub 2022 Nov 9. Biol Psychiatry. 2023. PMID: 36581494 Free PMC article.
CNTNAP2 stabilizes interneuron dendritic arbors through CASK.
Gao R, Piguel NH, Melendez-Zaidi AE, Martin-de-Saavedra MD, Yoon S, Forrest MP, Myczek K, Zhang G, Russell TA, Csernansky JG, Surmeier DJ, Penzes P. Gao R, et al. Among authors: piguel nh. Mol Psychiatry. 2018 Sep;23(9):1832-1850. doi: 10.1038/s41380-018-0027-3. Epub 2018 Apr 9. Mol Psychiatry. 2018. PMID: 29610457 Free PMC article.
Scribble1/AP2 complex coordinates NMDA receptor endocytic recycling.
Piguel NH, Fievre S, Blanc JM, Carta M, Moreau MM, Moutin E, Pinheiro VL, Medina C, Ezan J, Lasvaux L, Loll F, Durand CM, Chang K, Petralia RS, Wenthold RJ, Stephenson FA, Vuillard L, Darbon H, Perroy J, Mulle C, Montcouquiol M, Racca C, Sans N. Piguel NH, et al. Cell Rep. 2014 Oct 23;9(2):712-27. doi: 10.1016/j.celrep.2014.09.017. Epub 2014 Oct 9. Cell Rep. 2014. PMID: 25310985 Free article.
13 results