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The clinically available NMDA receptor antagonist, memantine, exhibits relative safety in the developing rat brain.
Int J Dev Neurosci. 2011 Nov;29(7):767-73. doi: 10.1016/j.ijdevneu.2011.05.005. Epub 2011 May 20.
Int J Dev Neurosci. 2011.
PMID: 21624454
Free PMC article.
NMDA receptor blockade with memantine attenuates white matter injury in a rat model of periventricular leukomalacia.
Manning SM, Talos DM, Zhou C, Selip DB, Park HK, Park CJ, Volpe JJ, Jensen FE.
Manning SM, et al. Among authors: selip db.
J Neurosci. 2008 Jun 25;28(26):6670-8. doi: 10.1523/JNEUROSCI.1702-08.2008.
J Neurosci. 2008.
PMID: 18579741
Free PMC article.
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Regional differences in susceptibility to hypoxic-ischemic injury in the preterm brain: exploring the spectrum from white matter loss to selective grey matter injury in a rat model.
Selip DB, Jantzie LL, Chang M, Jackson MC, Fitzgerald EC, Boll G, Murphy A, Jensen FE.
Selip DB, et al.
Neurol Res Int. 2012;2012:725184. doi: 10.1155/2012/725184. Epub 2012 Mar 15.
Neurol Res Int. 2012.
PMID: 22530125
Free PMC article.
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Developmental regulation of group I metabotropic glutamate receptors in the premature brain and their protective role in a rodent model of periventricular leukomalacia.
Jantzie LL, Talos DM, Selip DB, An L, Jackson MC, Folkerth RD, Deng W, Jensen FE.
Jantzie LL, et al. Among authors: selip db.
Neuron Glia Biol. 2010 Nov;6(4):277-88. doi: 10.1017/S1740925X11000111. Epub 2011 Dec 14.
Neuron Glia Biol. 2010.
PMID: 22169210
Free PMC article.
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