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Enhanced proteolytic clearance of plasma Aβ by peripherally administered neprilysin does not result in reduced levels of brain Aβ in mice.
Walker JR, Pacoma R, Watson J, Ou W, Alves J, Mason DE, Peters EC, Urbina HD, Welzel G, Althage A, Liu B, Tuntland T, Jacobson LH, Harris JL, Schumacher AM. Walker JR, et al. Among authors: urbina hd. J Neurosci. 2013 Feb 6;33(6):2457-64. doi: 10.1523/JNEUROSCI.3407-12.2013. J Neurosci. 2013. PMID: 23392674 Free PMC article.
Bicyclic carbamates as inhibitors of papain-like cathepsin proteases.
Epple R, Urbina HD, Russo R, Liu H, Mason D, Bursulaya B, Tumanut C, Li J, Harris JL. Epple R, et al. Among authors: urbina hd. Bioorg Med Chem Lett. 2007 Mar 1;17(5):1254-9. doi: 10.1016/j.bmcl.2006.12.014. Epub 2006 Dec 9. Bioorg Med Chem Lett. 2007. PMID: 17196818