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Year | Number of Results |
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2018 | 1 |
2021 | 1 |
2022 | 1 |
2023 | 2 |
2024 | 2 |
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Page 1
Antisense Oligonucleotide Silencing Reverses Abnormal Neurochemistry in Spinocerebellar Ataxia 3 Mice.
Ann Neurol. 2023 Oct;94(4):658-671. doi: 10.1002/ana.26713. Epub 2023 Aug 2.
Ann Neurol. 2023.
PMID: 37243335
α-Synuclein: Multiple pathogenic roles in trafficking and proteostasis pathways in Parkinson's disease.
Zalon AJ, Quiriconi DJ, Pitcairn C, Mazzulli JR.
Zalon AJ, et al.
Neuroscientist. 2024 Feb 29:10738584241232963. doi: 10.1177/10738584241232963. Online ahead of print.
Neuroscientist. 2024.
PMID: 38420922
Review.
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Impaired Autophagic-Lysosomal Fusion in Parkinson's Patient Midbrain Neurons Occurs through Loss of ykt6 and Is Rescued by Farnesyltransferase Inhibition.
Pitcairn C, Murata N, Zalon AJ, Stojkovska I, Mazzulli JR.
Pitcairn C, et al. Among authors: zalon aj.
J Neurosci. 2023 Apr 5;43(14):2615-2629. doi: 10.1523/JNEUROSCI.0610-22.2023. Epub 2023 Feb 14.
J Neurosci. 2023.
PMID: 36788031
Free PMC article.
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ASOs are an effective treatment for disease-associated oligodendrocyte signatures in premanifest and symptomatic SCA3 mice.
Schuster KH, Zalon AJ, DiFranco DM, Putka AF, Stec NR, Jarrah SI, Naeem A, Haque Z, Zhang H, Guan Y, McLoughlin HS.
Schuster KH, et al. Among authors: zalon aj.
Mol Ther. 2024 Feb 29:S1525-0016(24)00102-3. doi: 10.1016/j.ymthe.2024.02.033. Online ahead of print.
Mol Ther. 2024.
PMID: 38429929
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Impaired Oligodendrocyte Maturation Is an Early Feature in SCA3 Disease Pathogenesis.
Schuster KH, Zalon AJ, Zhang H, DiFranco DM, Stec NR, Haque Z, Blumenstein KG, Pierce AM, Guan Y, Paulson HL, McLoughlin HS.
Schuster KH, et al. Among authors: zalon aj.
J Neurosci. 2022 Feb 23;42(8):1604-1617. doi: 10.1523/JNEUROSCI.1954-20.2021. Epub 2022 Jan 18.
J Neurosci. 2022.
PMID: 35042771
Free PMC article.
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Antisense Oligonucleotide Therapy Targeted Against ATXN3 Improves Potassium Channel-Mediated Purkinje Neuron Dysfunction in Spinocerebellar Ataxia Type 3.
Bushart DD, Zalon AJ, Zhang H, Morrison LM, Guan Y, Paulson HL, Shakkottai VG, McLoughlin HS.
Bushart DD, et al. Among authors: zalon aj.
Cerebellum. 2021 Feb;20(1):41-53. doi: 10.1007/s12311-020-01179-7.
Cerebellum. 2021.
PMID: 32789747
Free PMC article.
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Loss of the Spinocerebellar Ataxia type 3 disease protein ATXN3 alters transcription of multiple signal transduction pathways.
Zeng L, Zhang D, McLoughlin HS, Zalon AJ, Aravind L, Paulson HL.
Zeng L, et al. Among authors: zalon aj.
PLoS One. 2018 Sep 19;13(9):e0204438. doi: 10.1371/journal.pone.0204438. eCollection 2018.
PLoS One. 2018.
PMID: 30231063
Free PMC article.
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