Dexmedetomidine is a potent and highly selective α2-adrenoreceptor agonist currently
utilized for continuous infusion for sedation/analgesia in the intensive care unit (ICU). …

Cancer is a disease with marked heterogeneity in both response to therapy and survival.
Clinical and histopathological characteristics have long determined prognosis and therapy. The …

Targeted therapy is considerably changing the treatment and prognosis of cancer.
Progressive understanding of the molecular mechanisms that regulate the establishment and …

Context: In patients with hypoxemic acute respiratory failure (ARF), randomized studies have
shown noninvasive positive pressure ventilation (NPPV) to be associated with lower rates …

With virtualization usage growing, the amount of RAM duplication in the same host across
different virtual machines possibly running the same software or handling the same data is …

An important target in the understanding of the pathogenesis of acute myeloid leukemias (AML)
relies on deciphering the molecular features of normal and leukemic hemopoietic …

The acquisition of the capacity to invade surrounding tissues confers a more malignant
phenotype to tumor cells and is necessary for the establishment of metastases. The …

The role of K + channel activity during cell cycle progression has become a research topic
of considerable interest. Blocking of K + channels inhibits the proliferation of many cell types, …

HERG K+ channels, besides contributing to regulate cardiac and neuronal excitability, are
preferentially expressed in tumour cell lines of different histogenesis, where their role in the …

Recent studies have led to considerable advancement in our understanding of the molecular
mechanisms that underlie the relentless cell growth and invasiveness of human gliomas. …