The rate of affective disorder is substantially higher in women than in men, and considerable
evidence points to the actions of ovarian hormones in mediating this disparity. In this …

Meta-analytic summaries of neuroimaging studies point to at least two major functional-anatomic
subdivisions within the anterior insula that contribute to the detection and processing of …

We tested two competing models for the brain basis of emotion, the basic emotion theory and
the conceptual act theory of emotion, using resting-state functional connectivity magnetic …

Large-scale intrinsic brain systems have been identified for exteroceptive senses (such as
sight, hearing and touch). We introduce an analogous system for representing sensations …

Decline in cognitive skills, especially in memory, is often viewed as part of “normal” aging.
Yet some individuals “age better” than others. Building on prior research showing that cortical …

Tenacity–persistence in the face of challenge–has received increasing attention, particularly
because it contributes to better academic achievement, career opportunities and health …

Research in humans and nonhuman animals indicates that social affiliation, and particularly
maternal bonding, depends on reward circuitry. Although numerous mechanistic studies in …

Recent theoretical and empirical work has highlighted the role of domain-general, large-scale
brain networks in generating emotional experiences. These networks are hypothesized to …

Oral contraceptive pills (OCs), which are used to prevent pregnancy by the majority of women
in the United States, contain steroid hormones that may affect the brain's structure and …

Background Clinical decision and patient care management in inflammatory bowel diseases
is largely based on the assessment of clinical symptoms, while the biomarkers currently in …