[HTML][HTML] Phosphorylation of Nedd4‐2 by Sgk1 regulates epithelial Na+ channel cell surface expression
…, C Tauxe, MA Thomas, C Münster, A Chraïbi… - The EMBO …, 2001 - embopress.org
The epithelial Na+ channel (ENaC) plays an essential role in the regulation of whole body
Na+ balance and blood pressure. The cell surface expression of this channel, a complex of …
Na+ balance and blood pressure. The cell surface expression of this channel, a complex of …
An epithelial serine protease activates the amiloride-sensitive sodium channel
V Vallet, A Chraibi, HP Gaeggeler, JD Horisberger… - Nature, 1997 - nature.com
Sodium balance, and ultimately blood pressure and extracellular fluid volume, is maintained
by precise regulation of the activity of the epithelial sodium channel (ENaC) 1 , 2 , 3 . In a …
by precise regulation of the activity of the epithelial sodium channel (ENaC) 1 , 2 , 3 . In a …
Protease Modulation of the Activity of the Epithelial Sodium Channel Expressed in Xenopus Oocytes
A Chraïbi, V Vallet, D Firsov, SK Hess… - The Journal of general …, 1998 - rupress.org
We have investigated the effect of extracellular proteases on the amiloride-sensitive Na +
current (I Na ) in Xenopus oocytes expressing the three subunits α, β, and γ of the rat or …
current (I Na ) in Xenopus oocytes expressing the three subunits α, β, and γ of the rat or …
Na self inhibition of human epithelial Na channel: temperature dependence and effect of extracellular proteases
A Chraïbi, JD Horisberger - The Journal of general physiology, 2002 - rupress.org
The regulation of the open probability of the epithelial Na + channel (ENaC) by the
extracellular concentration of Na + , a phenomenon called “Na + self inhibition,” has been well …
extracellular concentration of Na + , a phenomenon called “Na + self inhibition,” has been well …
[HTML][HTML] Functional expression of a pseudohypoaldosteronism type I mutated epithelial Na+ channel lacking the pore-forming region of its α subunit
The autosomal recessive form of type I pseudohypoaldosteronism (PHA-I) is an inherited
salt-losing syndrome resulting from diminution-of-function mutations in the 3 subunits of the …
salt-losing syndrome resulting from diminution-of-function mutations in the 3 subunits of the …
The chemokine CCL2 increases Nav1. 8 sodium channel activity in primary sensory neurons through a Gβγ-dependent mechanism
…, J Van Steenwinckel, N Beaudet, A Chraibi… - Journal of …, 2011 - Soc Neuroscience
Changes in function of voltage-gated sodium channels in nociceptive primary sensory neurons
participate in the development of peripheral hyperexcitability that occurs in neuropathic …
participate in the development of peripheral hyperexcitability that occurs in neuropathic …
[HTML][HTML] Proven infection-related sepsis induces a differential stress response early after ICU admission
Introduction Neuropeptides arginine-vasopressin (AVP), apelin (APL), and stromal-derived
factor-1α (SDF-1α) are involved in the dysfunction of the corticotropic axis observed in septic …
factor-1α (SDF-1α) are involved in the dysfunction of the corticotropic axis observed in septic …
[HTML][HTML] Functional up-regulation of Nav1.8 sodium channel in Aβ afferent fibers subjected to chronic peripheral inflammation
Background Functional alterations in the properties of Aβ afferent fibers may account for the
increased pain sensitivity observed under peripheral chronic inflammation. Among the …
increased pain sensitivity observed under peripheral chronic inflammation. Among the …
Modulation of canine cardiac sodium current by Apelin
…, C Antzelevitch, O Lesur, A Chraibi… - Journal of Molecular and …, 2010 - Elsevier
Apelin, a ligand of the G protein-coupled putative angiotensin II-like receptor (APJ-R), exerts
strong vasodilating, cardiac inotropic and chronotropic actions. Its expression is highly up-…
strong vasodilating, cardiac inotropic and chronotropic actions. Its expression is highly up-…
Epithelial sodium channel: a ligand-gated channel?
JD Horisberger, A Chraïbi - Nephron Physiology, 2004 - karger.com
The epithelial sodium channel (ENaC) is a key component of the transepithelial Na+ transport.
In epithelia, it is responsible for the maintenance of Na+ balance (which in turn controls …
In epithelia, it is responsible for the maintenance of Na+ balance (which in turn controls …