Gastrin is an important stimulant of acid secretion by gastric parietal cells and is structurally
related to the peptide hormone cholecystokinin (CCK). The pharmacologic properties of the …

The endocrine cells of the gut are a highly specialized mucosal cell subpopulation. Within the
gastrointestinal tract at least 14 different cell types produce a wide range of hormones with …

Food intake and body weight are determined by a complex interaction of regulatory pathways.
To elucidate the contribution of the endogenous peptide cholecystokinin, mice lacking …

Dopamine is an important neurotransmitter in the central nervous system of both Drosophila
and mammals. Despite the evolutionary distance, functional parallels exist between the fly …

BACKGROUND & AIMS: The cholecystokinin (CCK)-B/gastrin receptor is one of several
regulators of gastric acid secretion and mucosal growth. To elucidate the contribution of this …

In mammals, dopamine 2-like receptors are expressed in distinct pathways within the central
nervous system, as well as in peripheral tissues. Selected neuronal D2-like receptors play …

Although cholecystokinin A (CCK-A) receptors (CCK-AR) mediate the feeding inhibitory
actions of CCK in both rats and mice, the absence of CCK-AR results in species-specific …

Cholecystokinin (CCK) modulates contractility of the gallbladder, the sphincter of Oddi, and
the stomach. These effects are mediated through activation of gastrointestinal smooth muscle …

Glucagon-like peptide-1 (GLP-1) and its cognate receptor play an important physiological
role in maintaining blood glucose homeostasis. A GLP-1 receptor (GLP-1R) polymorphism in …

Erythrocytes from patients with homozygous hemoglobin C disease (CC cells) contain less K,
Na, and water than do erythrocytes from normal subjects that contain only hemoglobin A (…