User profiles for Alexander G. Murley
Alexander MurleyUniversity of Cambridge Verified email at nhs.net Cited by 684 |
Redefining the multidimensional clinical phenotypes of frontotemporal lobar degeneration syndromes
The syndromes caused by frontotemporal lobar degeneration have highly heterogeneous
and overlapping clinical features. There has been great progress in the refinement of clinical …
and overlapping clinical features. There has been great progress in the refinement of clinical …
GABA and glutamate deficits from frontotemporal lobar degeneration are associated with disinhibition
Behavioural disinhibition is a common feature of the syndromes associated with frontotemporal
lobar degeneration (FTLD). It is associated with high morbidity and lacks proven …
lobar degeneration (FTLD). It is associated with high morbidity and lacks proven …
Predicting loss of independence and mortality in frontotemporal lobar degeneration syndromes
Objective To test the hypothesis that in syndromes associated with frontotemporal lobar
degeneration, behavioural impairment predicts loss of functional independence and motor …
degeneration, behavioural impairment predicts loss of functional independence and motor …
Co‐occurrence of apathy and impulsivity in progressive supranuclear palsy
Background Apathy and impulsivity are common consequences of progressive supranuclear
palsy (PSP) and can worsen its prognosis. They can co‐exist in the same patients although …
palsy (PSP) and can worsen its prognosis. They can co‐exist in the same patients although …
Neurotransmitter deficits from frontotemporal lobar degeneration
Frontotemporal lobar degeneration causes a spectrum of complex degenerative disorders
including frontotemporal dementia, progressive supranuclear palsy and corticobasal …
including frontotemporal dementia, progressive supranuclear palsy and corticobasal …
Locus coeruleus integrity and the effect of atomoxetine on response inhibition in Parkinson's disease
Cognitive decline is a common feature of Parkinson’s disease, and many of these cognitive
deficits fail to respond to dopaminergic therapy. Therefore, targeting other neuromodulatory …
deficits fail to respond to dopaminergic therapy. Therefore, targeting other neuromodulatory …
Incidence of syndromes associated with frontotemporal lobar degeneration in 9 European countries
Importance Diagnostic incidence data for syndromes associated with frontotemporal lobar
degeneration (FTLD) in multinational studies are urgent in light of upcoming therapeutic …
degeneration (FTLD) in multinational studies are urgent in light of upcoming therapeutic …
[HTML][HTML] Reduced glutamate turnover in the putamen is linked with automatic habits in human cocaine addiction
Background The balance between goal-directed behavior and habits has been hypothesized
to be biased toward the latter in individuals with cocaine use disorder (CUD), suggesting …
to be biased toward the latter in individuals with cocaine use disorder (CUD), suggesting …
Locus Coeruleus Integrity Is Linked to Response Inhibition Deficits in Parkinson's Disease and Progressive Supranuclear Palsy
Parkinson's disease (PD) and progressive supranuclear palsy (PSP) both impair response
inhibition, exacerbating impulsivity. Inhibitory control deficits vary across individuals and are …
inhibition, exacerbating impulsivity. Inhibitory control deficits vary across individuals and are …
GABAergic cortical network physiology in frontotemporal lobar degeneration
The clinical syndromes caused by frontotemporal lobar degeneration are heterogeneous,
including the behavioural variant frontotemporal dementia (bvFTD) and progressive …
including the behavioural variant frontotemporal dementia (bvFTD) and progressive …