D-Aspartic acid: an endogenous amino acid with an important neuroendocrine role
A D'Aniello - Brain research reviews, 2007 - Elsevier
d-Aspartic acid (d-Asp), an endogenous amino acid present in vertebrates and invertebrates,
plays an important role in the neuroendocrine system, as well as in the development of the …
plays an important role in the neuroendocrine system, as well as in the development of the …
Occurrence of D‐aspartic acid and N‐methyl‐D‐aspartic acid in rat neuroendocrine tissues and their role in the modulation of luteinizing hormone and growth …
…, GH Fisher, A Milone, A Seleni, S D'Aniello… - The FASEB …, 2000 - Wiley Online Library
Using two specific and sensitive fluorometric/HPLC methods and a GC‐MS method, alone
and in combination with D‐aspartate oxidase, we have demonstrated for the first time that N‐…
and in combination with D‐aspartate oxidase, we have demonstrated for the first time that N‐…
[HTML][HTML] Biological role of D-amino acid oxidase and D-aspartate oxidase. Effects of D-amino acids.
A D'Aniello, G D'Onofrio, M Pischetola… - Journal of Biological …, 1993 - Elsevier
D-Amino acids administered to animals are absorbed by the intestine and transported through
the blood-stream to solid tissues where they are oxidized in vivo by D-amino acid oxidase …
the blood-stream to solid tissues where they are oxidized in vivo by D-amino acid oxidase …
Free D-aspartate and D-alanine in normal and Alzheimer brain
GH Fisher, A D'Aniello, A Vetere, L Padula… - Brain research …, 1991 - Elsevier
In this report we present evidence for the presence of free D-aspartic acid (D-Asp) and D-alanine
(D-Ala) in the white and gray matter of normal human brains and brains of individuals …
(D-Ala) in the white and gray matter of normal human brains and brains of individuals …
[HTML][HTML] The role and molecular mechanism of D-aspartic acid in the release and synthesis of LH and testosterone in humans and rats
…, A Soricelli, A D'Aniello, S Ronsini, G D'Aniello - Reproductive Biology …, 2009 - Springer
Background D-aspartic acid is an amino acid present in neuroendocrine tissues of
invertebrates and vertebrates, including rats and humans. Here we investigated the effect of this …
invertebrates and vertebrates, including rats and humans. Here we investigated the effect of this …
The Role of d-Aspartic Acid and N-Methyl-d-Aspartic Acid in the Regulation of Prolactin Release
G D'Aniello, A Tolino, A D'aniello, F Errico… - …, 2000 - academic.oup.com
In this study, using an enzymatic HPLC method in combination with d-aspartate oxidase, we
show that N-methyl-d-aspartate (NMDA) is present at nanomolar levels in rat nervous …
show that N-methyl-d-aspartate (NMDA) is present at nanomolar levels in rat nervous …
D‐Aspartic acid is a novel endogenous neurotransmitter
D‐Aspartic acid (D‐Asp) is present in invertebrate and vertebrate neuroendocrine tissues’
where it carries out important physiological functions and is implicated in nervous system …
where it carries out important physiological functions and is implicated in nervous system …
Further study on the specificity of D-amino acid oxidase and D-aspartate oxidase and time course for complete oxidation of D-amino acids.
A D'Aniello, A Vetere, L Petrucelli - Comparative biochemistry and …, 1993 - europepmc.org
1. D-Amino acid oxidase (D-AAO) oxidizes: D-Met, D-Pro, D-Phe, D-Tyr, D-Ile, D-Leu, D-Ala
and D-Val. D-Ser, D-Arg, D-His, D-norleucine and D-Trp are oxidized at a low rate. D-…
and D-Val. D-Ser, D-Arg, D-His, D-norleucine and D-Trp are oxidized at a low rate. D-…
D-aspartate prevents corticostriatal long-term depression and attenuates schizophrenia-like symptoms induced by amphetamine and MK-801
…, E Topo, G Fisone, A D'Aniello… - Journal of …, 2008 - Soc Neuroscience
Since their discovery in the mammalian CNS, d-aspartate and d-serine have aroused a
strong interest with regard to their role as putative neuromodulatory molecules. Whereas the …
strong interest with regard to their role as putative neuromodulatory molecules. Whereas the …
[HTML][HTML] Occurrence of D-aspartic acid in human seminal plasma and spermatozoa: possible role in reproduction
G D'Aniello, S Ronsini, F Guida, P Spinelli… - Fertility and sterility, 2005 - Elsevier
OBJECTIVE: To determine D-aspartic acid (D-Asp) in human seminal plasma and
spermatozoa in fertile and infertile donors. DESIGN: Prospective observation study. SETTING: …
spermatozoa in fertile and infertile donors. DESIGN: Prospective observation study. SETTING: …