Most of us sleep 7–8 h per night, and if we are deprived of sleep our performance suffers
greatly; however, a few do well with just 3–4 h of sleep—a trait that seems to run in families. …

Calcium-activated potassium channels mediate many biologically important functions in
electrically excitable cells. Despite recent progress in the molecular analysis of voltage-…

Previous behavioral, electrophysiological, pharmacological, and genetic studies of mutatlons
of the para locus in Drosophila melanogaster suggested that these mutations alter the …

The mle napts mutation causes temperature-dependent blockade of action potentials
resulting from decreased abundance of para-encoded Na + channels. Although maleless (mle) …

Many of the signaling properties of neurons and other electrically excitable cells are determined
by a diverse family of potassium channels. A number of genes that encode potassium …

Soluble N-ethylmaleimide-sensitive fusion attachment protein receptor (SNARE)-mediated
fusion of synaptic vesicles with the presynaptic-plasma membrane is essential for …

In contrast to other members of the Eag family of voltage-gated, outwardly rectifying potassium
channels, the human eag-related gene (HERG) has now been shown to encode an …

We have identified a conserved family of genes related to Drosophila eag, which encodes a
distinct type of voltage-activated K+ channel. Three related genes were recovered in …

… Troy Littleton*†‡ and Barry Ganetzky† *Center for Learning and Memory and Department of
… to be wired into complex computational circuits that and Ganetzky, 1992). The Drosophila …

Clathrin-mediated endocytosis is thought to involve the activity of the clathrin adaptor protein
AP180. However, the role of this protein in endocytosis in vivo remains unknown. Here, we …