User profiles for Bryony Winters
Bryony L WintersPostdoctoral Research Fellow, University of Sydney Verified email at sydney.edu.au Cited by 571 |
[HTML][HTML] Opioid-sparing effect of cannabinoids for analgesia: an updated systematic review and meta-analysis of preclinical and clinical studies
Cannabinoid co-administration may enable reduced opioid doses for analgesia. This updated
systematic review on the opioid-sparing effects of cannabinoids considered preclinical …
systematic review on the opioid-sparing effects of cannabinoids considered preclinical …
[HTML][HTML] Intracellular oligomeric amyloid-beta rapidly regulates GluA1 subunit of AMPA receptor in the hippocampus
The acute neurotoxicity of oligomeric forms of amyloid-β 1-42 (Aβ) is implicated in the
pathogenesis of Alzheimer’s disease (AD). However, how these oligomers might first impair …
pathogenesis of Alzheimer’s disease (AD). However, how these oligomers might first impair …
Muscarinic receptors induce LTD of NMDAR EPSCs via a mechanism involving hippocalcin, AP2 and PSD-95
Although muscarinic acetylcholine receptors (mAChRs) and NMDA receptors (NMDARs) are
important for synaptic plasticity, learning and memory, the manner in which they interact is …
important for synaptic plasticity, learning and memory, the manner in which they interact is …
[HTML][HTML] Endogenous opioids regulate moment-to-moment neuronal communication and excitability
BL Winters, GC Gregoriou, SA Kissiwaa… - Nature …, 2017 - nature.com
Fear and emotional learning are modulated by endogenous opioids but the cellular basis
for this is unknown. The intercalated cells (ITCs) gate amygdala output and thus regulate the …
for this is unknown. The intercalated cells (ITCs) gate amygdala output and thus regulate the …
Mechanisms of endocannabinoid control of synaptic plasticity
BL Winters, CW Vaughan - Neuropharmacology, 2021 - Elsevier
The endogenous cannabinoid transmitter system regulates synaptic transmission throughout
the nervous system. Unlike conventional transmitters, specific stimuli induce synthesis of …
the nervous system. Unlike conventional transmitters, specific stimuli induce synthesis of …
Oral efficacy of Δ (9)-tetrahydrocannabinol and cannabidiol in a mouse neuropathic pain model
…, J Harley, SL Casey, AC Vaughan, BL Winters… - …, 2021 - Elsevier
The psychoactive and non-psychoactive constituents of cannabis, Δ9-tetrahydrocannabinol (THC)
and cannabidiol (CBD), have synergistic analgesic efficacy in animal models of …
and cannabidiol (CBD), have synergistic analgesic efficacy in animal models of …
[HTML][HTML] Intrathecal actions of the cannabis constituents Δ (9)-tetrahydrocannabinol and cannabidiol in a mouse neuropathic pain model
SL Casey, VA Mitchell, EE Sokolaj, BL Winters… - International Journal of …, 2022 - mdpi.com
(1) Background: The psychoactive and non-psychoactive constituents of cannabis, Δ9-tetrahydrocannabinol
(THC) and cannabidiol (CBD), synergistically reduce allodynia in various …
(THC) and cannabidiol (CBD), synergistically reduce allodynia in various …
Cannabinoids and opioids differentially target extrinsic and intrinsic GABAergic inputs onto the periaqueductal grey descending pathway
The midbrain periaqueductal gray (PAG) plays a central role in pain modulation via
descending pathways. Opioids and cannabinoids are thought to activate these descending …
descending pathways. Opioids and cannabinoids are thought to activate these descending …
Opioid presynaptic disinhibition of the midbrain periaqueductal grey descending analgesic pathway
BK Lau, BL Winters… - British journal of …, 2020 - Wiley Online Library
Background and Purpose The midbrain periaqueductal grey (PAG) plays a central role in
modulating pain through a descending pathway that projects indirectly to the spinal cord via …
modulating pain through a descending pathway that projects indirectly to the spinal cord via …
Disrupted prediction error links excessive amygdala activation to excessive fear
A Sengupta, B Winters, EE Bagley… - Journal of …, 2016 - Soc Neuroscience
Basolateral amygdala (BLA) is critical for fear learning, and its heightened activation is widely
thought to underpin a variety of anxiety disorders. Here we used chemogenetic techniques …
thought to underpin a variety of anxiety disorders. Here we used chemogenetic techniques …