Caenorhabditis elegans levamisole resistance geneslev-1, unc-29, and unc-38 encode functional nicotinic acetylcholine receptor subunits

…, MD Squire, TM Barnes, C Tornoe… - Journal of …, 1997 - Soc Neuroscience
We show that three of the eleven genes of the nematodeCaenorhabditis elegans that
mediate resistance to the nematocide levamisole and to other cholinergic agonists encode …

Lophotoxin-insensitive nematode nicotinic acetylcholine receptors

C Tornøe, L Holden-Dye, C Garland… - Journal of …, 1996 - journals.biologists.com
Nematode nicotinic acetylcholine receptors (nAChRs) are molecular targets of several
anthelmintic drugs. Studies to date on Caenorhabditis elegans and Ascaris suum have …

[BOOK][B] Biological Science: exploring the science of life

A Goodenough, J Scott, G Cameron, D Hawkins… - 2022 - books.google.com
… Dr Jonathan RM Thacker, Senior Lecturer, Biological Sciences, University of the West of
Scotland Dr Camilla Tornoe, School of Life Sciences, University of Sussex Dr Halina Vaughan, …

Cardiovascular outcomes in patients who experienced a myocardial infarction while treated with liraglutide versus placebo in the LEADER trial

MA Nauck, K Tornøe, S Rasmussen… - Diabetes and …, 2018 - journals.sagepub.com
Objective: Animal studies demonstrated that glucagon-like peptide-1 receptor agonists
reduce myocardial necrosis following regional ischaemia induction. This effect may improve …

[PDF][PDF] Structure and function of the bacterial protein toxin phenomycin

BK Hansen, CK Larsen, JT Nielsen, EB Svenningsen… - Structure, 2020 - cell.com
Phenomycin is a bacterial mini-protein of 89 amino acids discovered more than 50 years
ago with toxicity in the nanomolar regime toward mammalian cells. The protein inhibits the …

Our tropical home: Danish'empire migrants' in the US Virgin Islands, 1917-1945

P ØSTERGAARD HANSEN - 2017 - cadmus.eui.eu
In 1917 Denmark sold its Caribbean colony to the United States. At a time when other European
empires were promoting social and economic reforms in the colonies, the Danish state …

Computational evolution of threonine-rich β-hairpin peptides mimicking specificity and affinity of antibodies

H Hu, C Kofoed, M Li, JPL Gonçalves… - ACS Central …, 2019 - ACS Publications
The development of recognition molecules with antibody-like properties is of great value to
the biotechnological and bioanalytical communities. The recognition molecules presented …

Glycomimetic based approach toward selective carbonic anhydrase inhibitors

D Pratesi, C Matassini, A Goti, A Angeli… - ACS Medicinal …, 2020 - ACS Publications
The synthesis of selective inhibitors of human carbonic anhydrases (hCAs) is of paramount
importance to avoid side effects derived from undesired interactions with isoforms not …

[HTML][HTML] The EndoC-βH1 cell line is a valid model of human beta cells and applicable for screenings to identify novel drug target candidates

VG Tsonkova, FW Sand, XA Wolf, LG Grunnet… - Molecular …, 2018 - Elsevier
Objective To characterize the EndoC-βH1 cell line as a model for human beta cells and
evaluate its beta cell functionality, focusing on insulin secretion, proliferation, apoptosis and ER …

[PDF][PDF] Exploring architectures displaying multimeric presentations of a trihydroxypiperidine iminosugar

C Matassini, S Mirabella, A Goti… - Beilstein Journal of …, 2015 - beilstein-journals.org
The synthesis of new multivalent architectures based on a trihydroxypiperidine α-fucosidase
inhibitor is reported herein. Tetravalent and nonavalent dendrimers were obtained by …