User profiles for Carissa A. Hansen

Carissa Anne Hansen

Columbia University
Verified email at columbia.edu
Cited by 110

[HTML][HTML] α-Synuclein-induced dysregulation of neuronal activity contributes to murine dopamine neuron vulnerability

…, JJ Lebowitz, B Ulm, M Bu, CA Hansen… - npj Parkinson's …, 2021 - nature.com
Pathophysiological damages and loss of function of dopamine neurons precede their
demise and contribute to the early phases of Parkinson’s disease. The presence of aberrant …

Levodopa-induced dyskinesia: A historical review of Parkinson's disease, dopamine, and modern advancements in research and treatment

CA Hansen, DR Miller, S Annarumma, CT Rusch… - Journal of …, 2022 - Springer
Over the past two decades, animal models of Parkinson’s disease (PD) have helped to
determine the plausible underlying mechanism of levo-dihydroxyphenylalanine (l-DOPA)-…

[HTML][HTML] TNFα increases tyrosine hydroxylase expression in human monocytes

…, G Shaw, A Collins, DR Miller, CA Hansen… - npj Parkinson's …, 2021 - nature.com
Most, if not all, peripheral immune cells in humans and animals express tyrosine hydroxylase
(TH), the rate limiting enzyme in catecholamine synthesis. Since TH is typically studied in …

Dopamine transporter is a master regulator of dopaminergic neural network connectivity

…, DT Guenther, AP Maurer, CA Hansen… - Journal of …, 2021 - Soc Neuroscience
Dopaminergic neurons of the substantia nigra pars compacta (SNC) and ventral tegmental
area (VTA) exhibit spontaneous firing activity. The dopaminergic neurons in these regions …

Novel insights in the pathophysiology of α-synuclein dysregulation on D2 receptor activity contributing to the vulnerability of dopamine neurons

…, J Azar, JJ Lebowitz, B Ulm, AM Bu, CA Hansen… - bioRxiv, 2021 - biorxiv.org
Pathophysiological damages and loss of function of dopamine neurons precedes their
demise and contributes to the early phases of Parkinson’s disease. The presence of aberrant …

TNFα increases tyrosine hydroxylase expression in human monocytes

…, A Collins, DR Miller, CA Hansen… - NPJ Parkinson's …, 2021 - search.proquest.com
Most, if not all, peripheral immune cells in humans and animals express tyrosine hydroxylase
(TH), the rate limiting enzyme in catecholamine synthesis. Since TH is typically studied in …

TNF increases Tyrosine Hydroxylase expression in human monocytes

…, M Badov, G Shaw, A Collins, DR Miller, CA Hansen… - bioRxiv, 2021 - biorxiv.org
Most, if not all, peripheral immune cells in humans and animals express tyrosine hydroxylase
(TH), the rate limiting enzyme in catecholamine synthesis. Since TH is typically studied in …

Author Correction: TNFα increases tyrosine hydroxylase expression in human monocytes

…, G Shaw, A Collins, DR Miller, CA Hansen… - npj Parkinson's …, 2021 - nature.com
The original version of the published Article had a mistake in the Competing Interests section.
The Competing Interests have been updated to the following: Malú Gámez Tansey is a co-…

Microglia senescence occurs in both substantia nigra and ventral tegmental area

…, D Miller, M Dacquel, W Hachmeister, C Hansen… - Glia, 2020 - Wiley Online Library
During aging humans lose midbrain dopamine neurons, but not all dopamine regions exhibit
vulnerability to neurodegeneration. Microglia maintain tissue homeostasis and neuronal …

[HTML][HTML] Methamphetamine regulation of activity and topology of ventral midbrain networks

…, JJ Lebowitz, DT Guenther, AJ Refowich, C Hansen… - PLoS …, 2019 - journals.plos.org
The ventral midbrain supports a variety of functions through the heterogeneity of neurons.
Dopaminergic and GABA neurons within this region are particularly susceptible targets of …