User profiles for Chelsea E. Bray

Chelsea Evelyn Bray

Medical Student
Verified email at osumc.edu
Cited by 503

Traumatic brain injury causes chronic cortical inflammation and neuronal dysfunction mediated by microglia

KG Witcher, CE Bray, T Chunchai, F Zhao… - Journal of …, 2021 - Soc Neuroscience
Traumatic brain injury (TBI) can lead to significant neuropsychiatric problems and
neurodegenerative pathologies, which develop and persist years after injury. Neuroinflammatory …

Traumatic brain injury‐induced neuronal damage in the somatosensory cortex causes formation of rod‐shaped microglia that promote astrogliosis and persistent …

KG Witcher, CE Bray, JE Dziabis, DB McKim… - Glia, 2018 - Wiley Online Library
Microglia undergo dynamic structural and transcriptional changes during the immune
response to traumatic brain injury (TBI). For example, TBI causes microglia to form rod‐shaped …

Amplified gliosis and interferon-associated inflammation in the aging brain following diffuse traumatic brain injury

LM Wangler, CE Bray, JM Packer, ZM Tapp… - Journal of …, 2022 - Soc Neuroscience
Traumatic brain injury (TBI) is associated with chronic psychiatric complications and increased
risk for development of neurodegenerative pathology. Aged individuals account for most …

Chronic cortical inflammation, cognitive impairment, and immune reactivity associated with diffuse brain injury are ameliorated by forced turnover of microglia

…, E Hans, ZM Tapp, J Packer, E Goodman… - Journal of …, 2022 - Soc Neuroscience
Traumatic brain injury (TBI) is associated with an increased risk of cognitive, psychiatric,
and neurodegenerative complications that may develop after injury. Increased microglial …

Interleukin-1 receptor on hippocampal neurons drives social withdrawal and cognitive deficits after chronic social stress

…, X Liu, KG Witcher, SM O'Neil, B Oliver, CE Bray… - Molecular …, 2021 - nature.com
Chronic stress contributes to the development of psychiatric disorders including anxiety and
depression. Several inflammatory-related effects of stress are associated with increased …

Sleep disruption exacerbates and prolongs the inflammatory response to traumatic brain injury

…, SM O'Neil, JE Dziabis, CE Bray… - Journal of …, 2020 - liebertpub.com
Traumatic brain injury (TBI) alters stress responses, which may influence neuroinflammation
and behavioral outcome. Sleep disruption (SD) is an understudied post-injury …

Impaired cortical neuronal homeostasis and cognition after diffuse traumatic brain injury are dependent on microglia and type I interferon responses

JM Packer, CE Bray, NB Beckman, LM Wangler… - Glia, 2024 - Wiley Online Library
Neuropsychiatric complications including depression and cognitive decline develop in the
years after traumatic brain injury (TBI), negatively affecting quality of life. Microglial and type 1 …

Comparison between midline and lateral fluid percussion injury in mice reveals prolonged but divergent cortical neuroinflammation

KG Witcher, JE Dziabis, CE Bray, AJ Gordillo… - Brain research, 2020 - Elsevier
Animal models are critical for determining the mechanisms mediating traumatic brain injury-induced
(TBI) neuropathology. Fluid percussion injury (FPI) is a widely used model of brain …

BAG3 attenuates tau hyperphosphorylation and gliosis induced by traumatic brain injury

…, JA Fitzgerald, K Karelina, CE Bray… - Alzheimer's & …, 2022 - Wiley Online Library
Background Alzheimer disease (AD) and traumatic brain injury (TBI) are two devastating brain
disorders with complex relationships. Growing evidence supports that early or middle life …

Correction: Interleukin-1 receptor on hippocampal neurons drives social withdrawal and cognitive deficits after chronic social stress.

…, KG Witcher, SM O'Neil, B Oliver, CE Bray… - Molecular …, 2021 - europepmc.org
Glutamate receptor antibodies in neurological diseases: anti-AMPA-GluR3 antibodies, anti-NMDA-NR1
antibodies, anti-NMDA-NR2A/B antibodies, anti-mGluR1 antibodies or anti-…