User profiles for Christian Steinhäuser
christian steinhäuserProfessor of Cellular Neurosciences, University of Bonn Verified email at ukbonn.de Cited by 19142 |
Reactive astrocyte nomenclature, definitions, and future directions
Reactive astrocytes are astrocytes undergoing morphological, molecular, and functional
remodeling in response to injury, disease, or infection of the CNS. Although this remodeling was …
remodeling in response to injury, disease, or infection of the CNS. Although this remodeling was …
Astrocyte dysfunction in neurological disorders: a molecular perspective
G Seifert, K Schilling, C Steinhäuser - Nature Reviews Neuroscience, 2006 - nature.com
Recent work on glial cell physiology has revealed that glial cells, and astrocytes in particular,
are much more actively involved in brain information processing than previously thought. …
are much more actively involved in brain information processing than previously thought. …
Functional changes in astroglial cells in epilepsy
DK Binder, C Steinhäuser - Glia, 2006 - Wiley Online Library
Epilepsy comprises a group of disorders characterized by the periodic occurrence of seizures,
and pathologic specimens from patients with temporal lobe epilepsy demonstrate marked …
and pathologic specimens from patients with temporal lobe epilepsy demonstrate marked …
News on glutamate receptors in glial cells
C Steinhäuser, V Gallo - Trends in neurosciences, 1996 - cell.com
Glutamate (Glu) receptors convey most of the excitatory synaptic transmission in the
mammalian CNS. Distinct Glu-receptor genes and different subtypes of glutamate-activated …
mammalian CNS. Distinct Glu-receptor genes and different subtypes of glutamate-activated …
Astrocyte dysfunction in temporal lobe epilepsy: K+ channels and gap junction coupling
C Steinhäuser, G Seifert, P Bedner - Glia, 2012 - Wiley Online Library
Astrocytes are endowed with the machinery to sense and respond to neuronal activity. Recent
work has demonstrated that astrocytes play important physiological roles in the CNS, eg, …
work has demonstrated that astrocytes play important physiological roles in the CNS, eg, …
Astrocytes contain a vesicular compartment that is competent for regulated exocytosis of glutamate
…, JL Galbete, G Seifert, C Steinhäuser… - Nature …, 2004 - nature.com
Astrocytes establish rapid cell-to-cell communication through the release of chemical transmitters.
The underlying mechanisms and functional significance of this release are, however, …
The underlying mechanisms and functional significance of this release are, however, …
Brain tumour cells interconnect to a functional and resistant network
…, Y Liao, P Häring, S Pusch, V Herl, C Steinhäuser… - Nature, 2015 - nature.com
Astrocytic brain tumours, including glioblastomas, are incurable neoplasms characterized
by diffusely infiltrative growth. Here we show that many tumour cells in astrocytomas extend …
by diffusely infiltrative growth. Here we show that many tumour cells in astrocytomas extend …
The impact of astrocytic gap junctional coupling on potassium buffering in the hippocampus
…, M Theis, K Willecke, C Steinhäuser - Journal of …, 2006 - Soc Neuroscience
Astrocytic gap junctions have been suggested to contribute to spatial buffering of potassium
in the brain. Direct evidence has been difficult to gather because of the lack of astrocyte-…
in the brain. Direct evidence has been difficult to gather because of the lack of astrocyte-…
Astrocyte uncoupling as a cause of human temporal lobe epilepsy
Glial cells are now recognized as active communication partners in the central nervous
system, and this new perspective has rekindled the question of their role in pathology. In the …
system, and this new perspective has rekindled the question of their role in pathology. In the …
Distinct types of astroglial cells in the hippocampus differ in gap junction coupling
A Wallraff, B Odermatt, K Willecke, C Steinhäuser - Glia, 2004 - Wiley Online Library
Previous studies have shown that two subpopulations of cells with astrocytic properties
coexist in the mouse hippocampus, which display distinct morphological and functional …
coexist in the mouse hippocampus, which display distinct morphological and functional …