Neuroscience has a long history of inferring brain function by examining the relationship
between brain injury and subsequent behavioral impairments. The primary advantage of this …

Brain lesion studies have been criticised for producing partly heterogeneous results; especially
the validity of statistical voxel-based lesion-behaviour mapping has been discussed. In …

Background Lacunes, microbleeds, enlarged perivascular spaces (EPVS), and white matter
hyperintensities (WMH) are brain imaging features of cerebral small vessel disease (SVD). …

Statistical voxel‐based lesion‐behavior mapping (VLBM) in neurological patients with brain
lesions is frequently used to examine the relationship between structure and function of the …

Human memory is dynamic and flexible but is also susceptible to distortions arising from
adaptive as well as pathological processes. Both accurate and false memory formation require …

Objective Although post-stroke cognitive deficit can significantly limit patient independence
and social re-integration, clinical routine predictors for this condition are lacking. ‘Cognitive …

Multivariate lesion behaviour mapping based on machine learning algorithms has recently
been suggested to complement the methods of anatomo‐behavioural approaches in …

Statistical lesion-symptom mapping is largely dominated by frequentist approaches with null
hypothesis significance testing. They are popular for mapping functional brain anatomy but …

In vivo tracking of white matter fibres catalysed a modern perspective on the pivotal role of
brain connectome disruption in neuropsychological deficits. However, the examination of …

Modelling behavioural deficits based on structural lesion imaging is a popular approach to
map functions in the human brain, and efforts to translationally apply lesion-behaviour …