Previous studies have identified two salt bridges in human CFTR chloride ion channels, Arg
352 -Asp 993 and Arg 347 -Asp 924 , that are required for normal channel function. In the …

The cystic fibrosis (CF) transmembrane conductance regulator (CFTR) bears six extracellular
loops (ECL1–6); ECL1 is the site of several mutations associated with CF. Mutation R117H …

Down syndrome cell adhesion molecules (dscam and dscaml1) are essential regulators of
neural circuit assembly, but their roles in vertebrate neural circuit function are still mostly …

The cystic fibrosis (CF) transmembrane conductance regulator (CFTR) is a chloride ion
channel, the dysfunction of which directly leads to the life-shortening disease CF. Extracellular …

Background Diet-related chronic diseases, such as diabetes mellitus, hypertension, and
hyperlipidemia have affected millions of individuals, resulting in disease-related complications …

The cystic fibrosis (CF) transmembrane conductance regulator (CFTR) is a chloride ion
channel, the dysfunction of which directly leads to the life-shortening disease CF. Extracellular …

Down Syndrome Cell Adhesion Molecules (dscam and dscaml1) are essential regulators of
neural circuit assembly, but their roles in vertebrate neural circuit function are still mostly …

Temple University, Philadelphia, PA, USA.‘Flucs’ are small membrane proteins widespread
in bacteria, single-celled eukaryotes, and plants. Only recently characterized, Flucs act as …

Temple University, Philadelphia, PA, USA.‘Flucs’ are small membrane proteins widespread
in bacteria, single-celled eukaryotes, and plants. Only recently characterized, Flucs act as …

The Down Syndrome Cell Adhesion Molecule (DSCAM) family proteins are neuronal cell
recognition 57 molecules that are essential for neural circuit assembly and neural patterning …