[PDF][PDF] Tracking cancer evolution reveals constrained routes to metastases: TRACERx renal
…, C Jones, H Rosenbaum, S Stanislaw, DL Burgess… - Cell, 2018 - cell.com
Clear-cell renal cell carcinoma (ccRCC) exhibits a broad range of metastatic phenotypes
that have not been systematically studied to date. Here, we analyzed 575 primary and 335 …
that have not been systematically studied to date. Here, we analyzed 575 primary and 335 …
Large expansion of the ATTCT pentanucleotide repeat in spinocerebellar ataxia type 10
T Matsuura, T Yamagata, DL Burgess, A Rasmussen… - Nature …, 2000 - nature.com
Spinocerebellar ataxia type 10 (SCA10; MIM 603516; refs 1, 2) is an autosomal dominant
disorder characterized by cerebellar ataxia and seizures. The gene SCA10 maps to a 3.8-cM …
disorder characterized by cerebellar ataxia and seizures. The gene SCA10 maps to a 3.8-cM …
[HTML][HTML] Mutation of the Ca2+ channel β subunit gene Cchb4 is associated with ataxia and seizures in the lethargic (lh) mouse
DL Burgess, JM Jones, MH Meisler, JL Noebels - Cell, 1997 - cell.com
Ca 2+ channel β subunits regulate voltage-dependent calcium currents through direct interaction
with α 1 subunits. The β- and α 1 -binding motifs are conserved, and all β subunits can …
with α 1 subunits. The β- and α 1 -binding motifs are conserved, and all β subunits can …
Mutation of a new sodium channel gene, Scn8a, in the mouse mutant 'motor endplate disease'
DL Burgess, DC Kohrman, J Galt, NW Plummer… - Nature …, 1995 - nature.com
The mouse neurological mutant ‘motor endplate disease’ (med) is characterized by early
onset progressive paralysis of the hind limbs, severe muscle atrophy, degeneration of Purkinje …
onset progressive paralysis of the hind limbs, severe muscle atrophy, degeneration of Purkinje …
[HTML][HTML] Targeted enrichment beyond the consensus coding DNA sequence exome reveals exons with higher variant densities
Background Enrichment of loci by DNA hybridization-capture, followed by high-throughput
sequencing, is an important tool in modern genetics. Currently, the most common targets for …
sequencing, is an important tool in modern genetics. Currently, the most common targets for …
[HTML][HTML] Whole exome capture in solution with 3 Gbp of data
MN Bainbridge, M Wang, DL Burgess, C Kovar… - Genome biology, 2010 - Springer
We have developed a solution-based method for targeted DNA capture-sequencing that is
directed to the complete human exome. Using this approach allows the discovery of greater …
directed to the complete human exome. Using this approach allows the discovery of greater …
Mutations in high-voltage-activated calcium channel genes stimulate low-voltage-activated currents in mouse thalamic relay neurons
Y Zhang, M Mori, DL Burgess… - Journal of …, 2002 - Soc Neuroscience
Ca 2+ currents, especially those activated at low voltages (LVA), influence burst generation
in thalamocortical circuitry and enhance the abnormal rhythmicity associated with absence …
in thalamocortical circuitry and enhance the abnormal rhythmicity associated with absence …
Genetic perturbation of the maize methylome
…, TF Madzima, AE Sloan, J Huang, DL Burgess… - The Plant …, 2014 - academic.oup.com
DNA methylation can play important roles in the regulation of transposable elements and
genes. A collection of mutant alleles for 11 maize (Zea mays) genes predicted to play roles in …
genes. A collection of mutant alleles for 11 maize (Zea mays) genes predicted to play roles in …
A triplet repeat expansion genetic mouse model of infantile spasms syndrome, Arx (GCG) 10+ 7, with interneuronopathy, spasms in infancy, persistent seizures, and …
MG Price, JW Yoo, DL Burgess, F Deng… - Journal of …, 2009 - Soc Neuroscience
Infantile spasms syndrome (ISS) is a catastrophic pediatric epilepsy with motor spasms,
persistent seizures, mental retardation, and in some cases, autism. One of its monogenic causes …
persistent seizures, mental retardation, and in some cases, autism. One of its monogenic causes …
A cluster of three novel Ca2+ channel γ subunit genes on chromosome 19q13. 4: evolution and expression profile of the γ subunit gene family
DL Burgess, LA Gefrides, PJ Foreman, JL Noebels - Genomics, 2001 - Elsevier
The CACNG1 gene on chromosome 17q24 encodes an integral membrane protein that was
originally isolated as the regulatory γ subunit of voltage-dependent Ca 2+ channels from …
originally isolated as the regulatory γ subunit of voltage-dependent Ca 2+ channels from …