Neither normal brain function nor the pathological processes involved in neurological diseases
can be adequately understood without knowledge of the release, uptake and metabolism …

Mechanisms that lead to the death of hair cells are reviewed. Exposure to noise, the use of
ototoxic drugs that damage the cochlea and old age are accompanied by hair cell death. …

Hearing loss is most often the result of hair-cell degeneration due to genetic abnormalities or
ototoxic and traumatic insults. In the postembryonic and adult mammalian auditory sensory …

… Hackney, Carole M., and David N. Furness. Mechanotransduction in vertebrate hair cells: …
It has been suggested that there may be myosin in the stereociliary rootlets (731, and Furness …

The extracellular levels of excitatory amino acids are kept low by the action of the glutamate
transporters. Glutamate/aspartate transporter (GLAST) and glutamate transporter-1 (GLT-1) …

Cross-links between stereocilia on guinea pig cochlear hair cells have been examined using
high resolution scanning (SEM) and transmission electron microscopy (TEM), confirming …

A number of putative neurotransmitter substances have been found in vertebrate taste buds.
Amongst these glutamate has been localized in fibres innervating the buds and uptake of …

Immunocytochemical studies have shown that protocadherin-15 (PCDH15) and cadherin-23
(CDH23) are associated with tip links, structures thought to gate the mechanotransducer …

Hair cells of the mammalian cochlea are specialized for the dynamic coding of sound stimuli.
The transduction of sound waves into electrical signals depends upon mechanosensitive …

MicroRNAs (miRNAs) are small noncoding RNAs able to regulate a broad range of protein-coding
genes involved in many biological processes. miR-96 is a sensory organ-specific …