User profiles for David J. Combs
David J Combs MD PhDInstructor in Anesthesia, Birgham and Women's Hospital Verified email at bwh.harvard.edu Cited by 151 |
Motor performance in rats exposed to severe forebrain ischemia: effect of fasting and 1, 3-butanediol.
DJ Combs, LG D'Alecy - Stroke, 1987 - Am Heart Assoc
Functional assessment of animals following experimental cerebral ischemia is often difficult
due to the passive nature of many neurologic exams. We attempted to increase the …
due to the passive nature of many neurologic exams. We attempted to increase the …
Moderate hypothermia reduces postischemic edema development and leukotriene production
RJ Dempsey, DJ Combs, ME Maley, DE Cowen… - …, 1987 - journals.lww.com
: Using the bilateral carotid artery occlusion model of cerebral ischemia in the gerbil, we
studied the effect of moderate hypothermia (30 to 31 [degrees] C) on the postischemic …
studied the effect of moderate hypothermia (30 to 31 [degrees] C) on the postischemic …
Relationship between plasma glucose, brain lactate, and intracellular pH during cerebral ischemia in gerbils.
DJ Combs, RJ Dempsey, M Maley, D Donaldson… - Stroke, 1990 - Am Heart Assoc
The dose-response relation between plasma glucose and brain lactate and the relation of
these parameters to intracellular pH during severe cerebral ischemia have not been well …
these parameters to intracellular pH during severe cerebral ischemia have not been well …
Morphometric evaluation of brain infarcts in rats and gerbils
…, BS Solik, RS Frank, PS Lacy, DJ Combs… - Journal of …, 1986 - Elsevier
The Levine rat prepartion, the gerbil stroke model, and appropriate control animals were
used to determine if the 2,3,5-triphenyltetrazolium chloride (TTC) would selectively identify …
used to determine if the 2,3,5-triphenyltetrazolium chloride (TTC) would selectively identify …
Glycolytic inhibition by 2-deoxyglucose reduces hyperglycemia-associated mortality and morbidity in the ischemic rat.
DJ Combs, DS Reuland, DB Martin, GB Zelenock… - Stroke, 1986 - Am Heart Assoc
Numerous laboratories have shown that hyperglycemia increases cerebral ischemic
damage. This presumably results from increased lactate production and accumulation during …
damage. This presumably results from increased lactate production and accumulation during …
Validation of algorithms to identify adverse perinatal outcomes in the Medicaid Analytic Extract database
…, D Bartels, S Burns, DJ Combs, J Cottral… - … and drug safety, 2020 - Wiley Online Library
Background The Medicaid Analytic eXtract (MAX) is a health care utilization database from
publicly insured individuals that has been used for studies of drug safety in pregnancy. Claims…
publicly insured individuals that has been used for studies of drug safety in pregnancy. Claims…
Tuning voltage-gated channel activity and cellular excitability with a sphingomyelinase
DJ Combs, HG Shin, Y Xu, Y Ramu, Z Lu - Journal of General …, 2013 - rupress.org
Voltage-gated ion channels generate action potentials in excitable cells and help set the
resting membrane potential in nonexcitable cells like lymphocytes. It has been difficult to …
resting membrane potential in nonexcitable cells like lymphocytes. It has been difficult to …
Extended peptoids: a new class of oligomers based on aromatic building blocks
Peptoids (N-substituted polyglycines) represent a class of bioinspired oligomers that have
unique physical and structural properties. Here, we report the construction of ‘extended …
unique physical and structural properties. Here, we report the construction of ‘extended …
Post-translational regulation and nuclear entry of TIMELESS and PERIOD are affected in new timeless mutant
The molecular circadian clock consists of a feedback loop in which canonical clock proteins
negatively regulate transcription of their own genes. Timed nuclear entry of these proteins is …
negatively regulate transcription of their own genes. Timed nuclear entry of these proteins is …
Difluoromethylornithine decreases postischemic brain edema and blood-brain barrier breakdown
MP Schmitz, DJ Combs, RJ Dempsey - Neurosurgery, 1993 - journals.lww.com
BRAIN POLYAMINES HAVE been associated with posttraumatic vasogenic edema and
blood-brain barrier (BBB) breakdown seen in some models of brain injury. We hypothesized that …
blood-brain barrier (BBB) breakdown seen in some models of brain injury. We hypothesized that …