User profiles for David R. Soll

David R. Soll

Professor, University of Iowa
Verified email at uiowa.edu
Cited by 32719

High-Frequency Switching of Colony Morphology in Candida albicans

B Slutsky, J Buffo, DR Soll - Science, 1985 - science.org
The pathogenic yeast Candida albicans switches heritably and at high frequency between
at least seven general phenotypes identified by colony morphology on agar. Spontaneous …

High-frequency switching in Candida albicans

DR Soll - Clinical Microbiology Reviews, 1992 - Am Soc Microbiol
Most strains of Candida albicans are capable of switching frequently and reversibly between
a number of phenotypes distinguishable by colony morphology. A number of different …

The ins and outs of DNA fingerprinting the infectious fungi

DR Soll - Clinical Microbiology Reviews, 2000 - Am Soc Microbiol
DNA fingerprinting methods have evolved as major tools in fungal epidemiology. However,
no single method has emerged as the method of choice, and some methods perform better …

A characterization of pH-regulated dimorphism in Candida albicans

J Buffo, MA Herman, DR Soll - Mycopathologia, 1984 - Springer
When cells of the dimorphic yeast Candida albicans are grown to stationary phase in defined
liquid medium at 25C, they accumulate as singlets in G l of the cell cycle. When these …

Cutting edge: Candida albicans hyphae formation triggers activation of the Nlrp3 inflammasome

S Joly, N Ma, JJ Sadler, DR Soll, SL Cassel… - The Journal of …, 2009 - journals.aai.org
The proinflammatory cytokine IL-1β plays an important role in antifungal immunity; however,
the mechanisms by which fungal pathogens trigger IL-1β secretion are unclear. In this study …

In Candida albicans, White-Opaque Switchers Are Homozygous for Mating Type

…, MG Miller, AD Johnson, MA Pfaller, DR Soll - Genetics, 2002 - academic.oup.com
The relationship between the configuration of the mating type locus (MTL) and white-opaque
switching in Candida albicans has been examined. Seven genetically unrelated clinical …

Misexpression of the Opaque-Phase-Specific GenePEP1 (SAP1) in the White Phase of Candida albicans Confers Increased Virulence in a Mouse Model of …

…, T Srikantha, K Daniels, J McCoy, DR Soll - Infection and …, 1999 - Am Soc Microbiol
Candida albicans WO-1 switches reversibly and at high frequency between a white and an
opaque colony-forming phenotype that includes dramatic changes in cell morphology and …

Unique phenotype of opaque cells in the white-opaque transition of Candida albicans

JM Anderson, DR Soll - Journal of bacteriology, 1987 - Am Soc Microbiol
Select strains of Candida albicans switch reversibly and at extremely high frequency between
a white and an opaque colony-forming phenotype, which has been referred to as the white…

Frequency, intensity, species, and strains of oral Candida vary as a function of host age

…, SR Lockhart, K Vargas, DR Soll - Journal of clinical …, 1996 - Am Soc Microbiol
While the age of the host has been suggested as a determining factor in yeast carriage, no
studies in which the genetic relatedness of isolates has been assessed in combination with …

Multilocus Sequence Typing of Candidaglabrata Reveals Geographically EnrichedClades

…, C Pujol, DW Denning, DR Soll… - Journal of clinical …, 2003 - Am Soc Microbiol
The haploid pathogenic yeast Candida glabrata is the second most common Candida
species isolated from cases of bloodstream infection. The clinical relevance of C. glabrata is …