[HTML][HTML] Genetically targeted optical electrophysiology in intact neural circuits

G Cao, J Platisa, VA Pieribone, D Raccuglia, M Kunst… - Cell, 2013 - cell.com
Nervous systems process information by integrating the electrical activity of neurons in
complex networks. This motivates the long-standing interest in using optical methods to …

[PDF][PDF] Calcitonin gene-related peptide neurons mediate sleep-specific circadian output in Drosophila

M Kunst, ME Hughes, D Raccuglia, M Felix, M Li… - Current Biology, 2014 - cell.com
Background Imbalances in amount and timing of sleep are harmful to physical and mental
health. Therefore, the study of the underlying mechanisms is of great biological importance. …

[PDF][PDF] Network-specific synchronization of electrical slow-wave oscillations regulates sleep drive in Drosophila

D Raccuglia, S Huang, A Ender, MM Heim, D Laber… - Current Biology, 2019 - cell.com
Slow-wave rhythms characteristic of deep sleep oscillate in the delta band (0.5–4 Hz) and
can be found across various brain regions in vertebrates. Across phyla, however, an …

Presynaptic GABA receptors mediate temporal contrast enhancement in Drosophila olfactory sensory neurons and modulate odor-driven behavioral kinetics

D Raccuglia, LY McCurdy, M Demir, S Gorur-Shandilya… - Eneuro, 2016 - eneuro.org
Contrast enhancement mediated by lateral inhibition within the nervous system enhances
the detection of salient features of visual and auditory stimuli, such as spatial and temporal …

Focal uncaging of GABA reveals a temporally defined role for GABAergic inhibition during appetitive associative olfactory conditioning in honeybees

D Raccuglia, U Mueller - Learning & Memory, 2013 - learnmem.cshlp.org
Throughout the animal kingdom, the inhibitory neurotransmitter γ-aminobutyric acid (GABA)
is a key modulator of physiological processes including learning. With respect to associative …

The neural architecture of sleep regulation – insights from Drosophila

R Suárez-Grimalt, D Raccuglia - Neuroforum, 2021 - degruyter.com
… and Davide RaccugliaDavide Raccuglia is currently a research scientist and lecturer at
the Institute of Neurophysiology at the Charité in Berlin. Davide studied Human and Molecular …

Temporal integration of cholinergic and GABAergic inputs in isolated insect mushroom body neurons exposes pairing-specific signal processing

D Raccuglia, U Mueller - Journal of Neuroscience, 2014 - Soc Neuroscience
GABAergic modulation of neuronal activity plays a crucial role in physiological processes
including learning and memory in both insects and mammals. During olfactory learning in …

[HTML][HTML] Goggatomy: a method for opening small cuticular compartments in arthropods for physiological experiments

AR Kay, D Raccuglia, J Scholte, MN Nitabach… - Frontiers in …, 2016 - frontiersin.org
Most sense organs of arthropods are ensconced in small exoskeletal compartments that
hinder direct access to plasma membranes. We have developed a method for exposing live …

[HTML][HTML] NOSA, an analytical toolbox for multicellular optical electrophysiology

…, DA Storace, JRP Geiger, D Raccuglia - Frontiers in …, 2020 - frontiersin.org
Understanding how neural networks generate activity patterns and communicate with each
other requires monitoring the electrical activity from many neurons simultaneously. Perfectly …

A new method to characterize function of the Drosophila heart by means of optical flow

…, V Richter, D Hilpert, D Raccuglia… - Journal of …, 2017 - journals.biologists.com
The minuteness of Drosophila poses a challenge to quantify performance of its tubular heart
and computer-aided analysis of its beating heart has evolved as a resilient compromise …