Aluminum, iron, and zinc ions promote aggregation of physiological concentrations of β‐amyloid peptide
…, JR Ghilardi, S Rogers, E DeMaster… - Journal of …, 1993 - Wiley Online Library
A major pathological feature of Alzheimer's disease (AD) is the presence of a high density of
amyloid plaques in the brain tissue of patients. The plaques are predominantly composed of …
amyloid plaques in the brain tissue of patients. The plaques are predominantly composed of …
Receptor endocytosis and dendrite reshaping in spinal neurons after somatosensory stimulation
PW Mantyh, E DeMaster, A Malhotra, Ghilardi… - Science, 1995 - science.org
In vivo somatosensory stimuli evoked the release of substance P from primary afferent neurons
that terminate in the spinal cord and stimulated endocytosis of substance P receptors in …
that terminate in the spinal cord and stimulated endocytosis of substance P receptors in …
Reaction between S-Nitrosothiols and Thiols: Generation of Nitroxyl (HNO) and Subsequent Chemistry
…, J Hyun, JM Fukuto, FN Shirota, EG DeMaster… - Biochemistry, 1998 - ACS Publications
S-Nitrosothiols have been implicated to play key roles in a variety of physiological processes.
The potential physiological importance of S-nitrosothiols prompted us to examine their …
The potential physiological importance of S-nitrosothiols prompted us to examine their …
Stable compounds of cigarette smoke induce endothelial superoxide anion production via NADPH oxidase activation
EA Jaimes, EG DeMaster, RX Tian… - … , thrombosis, and vascular …, 2004 - Am Heart Assoc
Objective— Endothelial dysfunction is an early manifestation of cigarette smoke (CS) toxicity.
We have previously demonstrated that CS impairs nitric oxide (NO)-mediated endothelial …
We have previously demonstrated that CS impairs nitric oxide (NO)-mediated endothelial …
Oxidation of hydrogen sulfide and methanethiol to thiosulfate by rat tissues: a specialized function of the colonic mucosa
J Furne, J Springfield, T Koenig, E DeMaster… - Biochemical …, 2001 - Elsevier
Colonic bacteria release large quantities of the highly toxic thiols hydrogen sulfide (H 2 S)
and methanethiol (CH 3 SH). These gases rapidly permeate the colonic mucosa, and tissue …
and methanethiol (CH 3 SH). These gases rapidly permeate the colonic mucosa, and tissue …
[HTML][HTML] Detoxification of hydrogen sulfide and methanethiol in the cecal mucosa
…, J Springfield, F Suarez, E DeMaster - The Journal of …, 1999 - Am Soc Clin Investig
… As shown in Figure 1e, hepatic tissue metabolized H 2 S and CH 3 SH, but at a much slower
rate than was observed with cecal mucosa, and there was no detectable metabolism of CH …
rate than was observed with cecal mucosa, and there was no detectable metabolism of CH …
Cigarette smoke-induced endothelium dysfunction: role of superoxide anion
L Raij, EG DeMaster, EA Jaimes - Journal of hypertension, 2001 - journals.lww.com
Objectives Cigarette smoking is strongly associated with coronary artery disease and
atherosclerosis. While smoking has been shown to impair endothelium-dependent vasorelaxation, …
atherosclerosis. While smoking has been shown to impair endothelium-dependent vasorelaxation, …
Mechanisms of inhibition of aldehyde dehydrogenase by nitroxyl, the active metabolite of the alcohol deterrent agent cyanamide
EG DeMaster, B Redfern, HT Nagasawa - Biochemical pharmacology, 1998 - Elsevier
Nitroxyl, produced in the bioactivation of the alcohol deterrent agent cyanamide, is a potent
inhibitor of aldehyde dehydrogenase (AlDH); however, the mechanism of inhibition of AlDH …
inhibitor of aldehyde dehydrogenase (AlDH); however, the mechanism of inhibition of AlDH …
Effect of regulating cholesterol biosynthesis on breath isoprene excretion in men
…, TJ Besse, WC Duane, C Dean Evans, EG DeMaster - Lipids, 1993 - Springer
Isoprene is a normal constituent of human breath and may be derived from the cholesterol
synthetic pathway. Acute and chronic lovastatin and a cholesterol-supplemented diet were …
synthetic pathway. Acute and chronic lovastatin and a cholesterol-supplemented diet were …
Reaction of nitroxyl, an aldehyde dehydrogenase inhibitor, with N-acetyl-L-cysteine
DW Shoeman, FN Shirota, EG DeMaster… - Alcohol, 2000 - Elsevier
Nitroxyl (HNO) is the aldehyde dehydrogenase (AlDH) inhibitor produced by catalase action
on cyanamide. Incubation of N-acetyl-L-cysteine (NAC), a reagent with a free sulfhydryl …
on cyanamide. Incubation of N-acetyl-L-cysteine (NAC), a reagent with a free sulfhydryl …