Amyloid-β peptide (Aβ) is a central player in the pathogenesis and diagnosis of Alzheimer
disease. It aggregates to form the core of Alzheimer disease-associated plaques found in …

Acute intoxication with large doses of ammonia leads to rapid death. The main mechanism
for ammonia elimination in brain is its reaction with glutamate to form glutamine. This reaction …

The first human transfusion was performed by the pioneer Dr Jean-Baptiste Denis in France
in 1667 and now, three centuries later, around 50 millions blood units are transfused every …

… Mitochondrial and cytosolic fractions were isolated essentially by the Lai and Clark's method
as described by Kosenko et aZ..["] Protein was determined by the method of Lowry et QZ.['I …

… rats in the following experiments: (A, B) the control rat after the icv injection of 0.9% NaCl (1st,
3d, and 5th trials); (C, D) the rat after the icv injection of the aggregated A 25−35; (E, F) the …

Injection of large doses of ammonia into rats leads to depletion of brain ATP. However, the
molecular mechanism leading to ATP depletion is not clear. The aim of the present work was …

… Mitochondria were isolated essentially by the Lai and Clark’s method as described by
Kosenko et al [15]. Briefly, the … These results are in agreement with those of Kosenko et al. [17]. …

The effects of acute ammonia intoxication on reactive oxygen species production by different
sources in rat brain were studied. Ammonia intoxication in vivo leads to reduced activity of …

Acute administration of large doses of ammonia leads to the rapid death of animals. This
article reviews the role of excessive activation of N-methyl-d-aspartate (NMDA) receptors in the …

… et al. 1994) or after inhibition of NO synthase with nitroarginine (Kosenko et al. 1995), the
increase in glutamine content in brain is significantly higher than in rats injected only with …