Purpose of Review While immune checkpoint inhibitor (ICI) therapy has improved melanoma
patient outcomes, it has also resulted in the rise of unique immune-related adverse events (…

Background Identification of serum proteins that track with disease course in sarcoidosis may
have clinical and pathologic importance. We previously identified up-regulated transcripts …

Objectives Preoperative biliary stenting is required for patients with obstructive jaundice from
pancreatic adenocarcinoma who are receiving neoadjuvant chemotherapy. While in most …

NrCAM is a neural cell adhesion molecule of the L1 family that has been linked to autism
spectrum disorders, a disease spectrum in which abnormal thalamocortical connectivity may …

… Darnell1,2,* and Marcela V. Maus1,2 1Cellular Immunotherapy Program, Mass General
Cancer Center, Massachusetts General Hospital, Boston, MA, USA 2Harvard Medical School …

In this issue of Blood, Abramson et al 1 present follow-up data from TRANSCEND,
redemonstrating robust and ongoing responses from the largest pivotal cohort of CD19 chimeric …

Expression of the transcription factor interferon regulatory factor 4 (IRF4) is required for the
development of lung conventional DCs type 2 (cDC2s) that elicit Th2 responses, yet how …

In this issue of Blood, Bethge et al 1 present findings from the analysis of 356 patients
treated with axicabtagene ciloleucel (axi-cel) or tisagenlecleucel (tisa-cel) chimeric antigen …

Inflammation has been implicated in physical frailty, but its role in sensory impairment is
unclear. Given that olfactory impairment predicts dementia and mortality, determining the role of …

METHODS: We identified all patients of Massachusetts General Hospital (MGH) from 2013
to 2018 who underwent neoadjuvant chemotherapy and received ERCP with metal biliary …