TRPV1 (transient receptor potential vanilloid receptor subtype 1) is a member of the TRP
channel family gated by vanilloids, protons, and heat. Structurally, TRPV1 appears to be a …

Meganucleases cut long (>12 bp) unique sequences in genomes and can be used to
induce targeted genome engineering by homologous recombination in the vicinity of their …

The tumor suppressor gene p53 is mutated or deleted in over 50% of human tumors. As
functional p53 plays a pivotal role in protecting against cancer development, several strategies …

Non-structural NS2A protein of Dengue virus is essential for viral replication but poorly
characterized because of its high hydrophobicity. We have previously shown experimentally that …

Dengue virus C protein, essential in the dengue virus life cycle, possesses a segment,
peptide PepC, known to bind membranes composed of negatively charged phospholipids. To …

Ursolic acid (URS), an ursane-representative bioactive pentacyclic triterpene, is a plant
secondary metabolite presenting a great number of pharmacological beneficial properties. Due …

This dissertation focuses on the design of two enzymes, the Tobacco Etch Virus “Nuclear
Inclusion a” (NIa) endoprotease (TEV protease) and the Chlamydomonas reinhardtii I-CreI …

This dissertation focuses on the design of two enzymes, the Tobacco Etch Virus" Nuclear
inclusion a"(NIa) endoprotease (TEV protease) and the Chlamydomonas reinhardtii I-CreI …

El presente estudio pretende demostrar como el film “La Sociedad del Semáforo” bajo el
método de la técnica del realismo cinematográfico, refleja con crudeza la violación los …