User profiles for Eric J. Bellefroid

Eric J Bellefroid

Yale University
Verified email at yale.edu
Cited by 637

The evolutionarily conserved Krüppel-associated box domain defines a subfamily of eukaryotic multifingered proteins.

EJ Bellefroid, DA Poncelet, PJ Lecocq… - Proceedings of the …, 1991 - National Acad Sciences
We have previously shown that the human genome includes hundreds of genes coding for
putative factors related to the Krüppel zinc-finger protein, which regulates Drosophila …

Engineered Wnt ligands enable blood-brain barrier repair in neurological disorders

…, S Boutry, A de Kerchove d'Exaerde, EJ Bellefroid… - Science, 2022 - science.org
The blood-brain barrier (BBB) protects the central nervous system (CNS) from harmful blood-borne
factors. Although BBB dysfunction is a hallmark of several neurological disorders, …

Constraints on Paleoproterozoic atmospheric oxygen levels

EJ Bellefroid, AS Hood, PF Hoffman… - Proceedings of the …, 2018 - National Acad Sciences
The oxygenation of Earth’s surface environment dramatically altered key biological and
geochemical cycles and ultimately ushered in the rise of an ecologically diverse biosphere. …

[HTML][HTML] X-MyT1, a Xenopus C2HC-type zinc finger protein with a regulatory function in neuronal differentiation

EJ Bellefroid, C Bourguignon, T Hollemann, Q Ma… - Cell, 1996 - cell.com
X-MyT1 is a C2HC-type zinc finger protein that we find to be involved in the primary selection
of neuronal precursor cells in Xenopus. Expression of this gene is positively regulated by …

Neoproterozoic iron formation: An evaluation of its temporal, environmental and tectonic significance

…, DP Le Heron, FA Macdonald, EJ Bellefroid… - Chemical …, 2013 - Elsevier
Neoproterozoic iron formation (NIF) provides evidence for the widespread return of anoxic
and ferruginous basins during a time period associated with major changes in climate, …

A lithium-isotope perspective on the evolution of carbon and silicon cycles

…, NJ Planavsky, AS Hood, M Dellinger, EJ Bellefroid… - Nature, 2021 - nature.com
The evolution of the global carbon and silicon cycles is thought to have contributed to the
long-term stability of Earth’s climate 1 , 2 – 3 . Many questions remain, however, regarding the …

[HTML][HTML] Xiro3 encodes a Xenopus homolog of the Drosophila Iroquois genes and functions in neural specification

EJ Bellefroid, A Kobbe, P Gruss, T Pieler… - The EMBO …, 1998 - embopress.org
We have identified in Xenopus and in the mouse two highly related genes, Xiro3 and Irx3
respectively, that encode a Drosophila Iroquois‐related homeobox transcription factor. Xiro3 in …

[HTML][HTML] Vertebrate sensory ganglia: common and divergent features of the transcriptional programs generating their functional specialization

S Vermeiren, EJ Bellefroid, S Desiderio - Frontiers in Cell and …, 2020 - frontiersin.org
Sensory fibers of the peripheral nervous system carry sensation from specific sense structures
or use different tissues and organs as receptive fields, and convey this information to the …

Snowballs in Africa: sectioning a long-lived Neoproterozoic carbonate platform and its bathyal foreslope (NW Namibia)

…, PW Crockford, EB Hodgin, EJ Bellefroid… - Earth-Science …, 2021 - Elsevier
Otavi Group is a 1.5–3.5-km-thick epicontinental marine carbonate succession of Neoproterozoic
age, exposed in an 800-km-long Ediacaran−Cambrian fold belt that rims the SW cape …

Clustered organization of homologous KRAB zinc‐finger genes with enhanced expression in human T lymphoid cells.

EJ Bellefroid, JC Marine, T Ried, PJ Lecocq… - The EMBO …, 1993 - embopress.org
KRAB zinc‐finger proteins (KRAB‐ZFPs) constitute a large subfamily of ZFPs of the Krüppel
C2H2 type. KRAB (Krüppel‐associated box) is an evolutionarily conserved protein domain …