Previous studies have revealed the existence of a gene family that encodes a group of
neuronal nicotinic acetylcholine receptor (nAChR) subunits. Four members of this family have …

Three closely related genes, GluR1, GluR2, and GluR3, encode receptor subunits for the
excitatory neurotransmitter glutamate. The proteins encoded by the individual genes form …

We have isolated cDNAs encoding a glutamate receptor subunit, designated CIuR5, displaying
40%-41% amino acid identity with the kainate/AMPA receptor subunits CIuRl, GIuR2, …

DBA mice were chronically treated with nicotine by continuous intravenous infusion of 4.0
mg/kg/hr for 10 d. Drug-treated mice were tolerant to the acute effects of nicotine on locomotor …

Serotonin (5-hydroxytryptamine or 5-HT) is thought to regulate neurodevelopmental processes
through maternal–fetal interactions that have long-term mental health implications. It is …

The central serotonin (5-HT) neurotransmitter system is an important modulator of diverse
physiological processes and behaviors; however, the transcriptional mechanisms controlling …

The link between dysregulated serotonergic activity and depression and anxiety disorders
is well established, yet the molecular mechanisms underlying these psychopathologies are …

Serotonergic neurons project widely throughout the CNS and modulate many different brain
functions. Particularly important, but controversial, are the contributions of serotonin (5-HT) …

Serotonin (5-HT) plays a crucial neuromodulatory role in numerous physiological and
behavioral functions, and dysfunction of the serotonergic system has been implicated in several …

A family of genes coding for proteins homologous to the alpha subunit of the muscle nicotinic
acetylcholine receptor has been identified in the rat genome. These genes are transcribed …