Anomalies in prefrontal cortex (PFC) function are posited to underpin difficulties in learning
to suppress drug-seeking behavior during abstinence. Because group 1 metabotropic …

Poxvirus-based active immunotherapies mediate anti-tumor efficacy by triggering broad and
durable Th1 dominated T cell responses against the tumor. While monotherapy significantly …

The dramatic clinical benefit of immune checkpoint blockade for a fraction of cancer patients
suggests the potential for further clinical benefit in a broader cancer patient population by …

Background PROSTVAC®, an active immunotherapy currently studied for the treatment of
metastatic castration-resistant prostate cancer (mCRPC), consists of a heterologous prime-…

Motor cortex (M1) has been thought to form a continuous somatotopic homunculus extending
down the precentral gyrus from foot to face representations 1 , 2 , despite evidence for …

Abstract Treatment with poxvirus-based active immunotherapies shows evidence of robust
immune responses against a variety of tumor-associated antigens in preclinical and clinical …

Introduction Acute bacterial skin and skin structure infections (ABSSSIs) remain among the
most common infectious processes seen in the clinical setting. For patients with complicated …

Control over behavior is enabled by the brain's control networks, which interact with lower-level
sensory motor and default networks to regulate their functions. Such interactions are …

The human brain is organized into large-scale networks identifiable using resting-state
functional connectivity (RSFC). These functional networks correspond with broad cognitive …

Human functional MRI (fMRI) research primarily focuses on analyzing data averaged across
groups, which limits the detail, specificity, and clinical utility of fMRI resting-state functional …