User profiles for Frank Birklein

Frank Birklein

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Cited by 25458

Quantitative sensory testing: a comprehensive protocol for clinical trials

…, KA Campbell, C Schalber, S Caspari, F Birklein… - European journal of …, 2006 - Elsevier
We have compiled a comprehensive QST protocol as part of the German Research Network
on Neuropathic Pain (DFNS) using well established tests for nearly all aspects of …

Validation of proposed diagnostic criteria (the “Budapest Criteria”) for complex regional pain syndrome

RN Harden, S Bruehl, RSGM Perez, F Birklein… - Pain, 2010 - Elsevier
Current IASP diagnostic criteria for CRPS have low specificity, potentially leading to
overdiagnosis. This validation study compared current IASP diagnostic criteria for CRPS to …

Clinical features and pathophysiology of complex regional pain syndrome

J Marinus, GL Moseley, F Birklein, R Baron… - The Lancet …, 2011 - thelancet.com
A complex regional pain syndrome (CRPS)—multiple system dysfunction, severe and often
chronic pain, and disability—can be triggered by a minor injury, a fact that has fascinated …

Patterns of cortical reorganization in complex regional pain syndrome

…, HO Handwerker, B Neundorfer, F Birklein - Neurology, 2003 - AAN Enterprises
Objective: To use magnetoencephalography to assess possible cortical reorganization in
the primary somatosensory cortex (S1) of patients with complex regional pain syndrome (CRPS…

Cortical reorganization during recovery from complex regional pain syndrome

…, HO Handwerker, B Neundörfer, F Birklein - Neurology, 2004 - AAN Enterprises
Objective: To characterize reorganization of the primary somatosensory cortex (S1) during
healing process in complex regional pain syndrome (CRPS). Background: Recently, the …

The motor system shows adaptive changes in complex regional pain syndrome

C Maihöfner, R Baron, R DeCol, A Binder, F Birklein… - Brain, 2007 - academic.oup.com
The complex regional pain syndrome (CRPS) is a disabling neuropathic pain condition that
may develop following injuries of the extremities. In the present study we sought to …

[HTML][HTML] Ambient air pollution increases the risk of cerebrovascular and neuropsychiatric disorders through induction of inflammation and oxidative stress

O Hahad, J Lelieveld, F Birklein, K Lieb… - International journal of …, 2020 - mdpi.com
Exposure to ambient air pollution is a well-established determinant of health and disease.
The Lancet Commission on pollution and health concludes that air pollution is the leading …

Differential expression patterns of cytokines in complex regional pain syndrome

N Üçeyler, T Eberle, R Rolke, F Birklein, C Sommer - Pain, 2007 - Elsevier
Complex regional pain syndromes (CRPS) are characterized by persistent and severe pain
after trauma or surgery. Neuro-immune alterations are assumed to play a pathophysiological …

Neuropeptides, neurogenic inflammation and complex regional pain syndrome (CRPS)

F Birklein, M Schmelz - Neuroscience letters, 2008 - Elsevier
This review explains symptoms and nature of neuropeptide signaling and its importance for
clinical symptoms of CRPS. Neurogenic inflammation regularly accompanies excitation of …

Test–retest and interobserver reliability of quantitative sensory testing according to the protocol of the German Research Network on Neuropathic Pain (DFNS): a multi …

C Geber, T Klein, S Azad, F Birklein, J Gierthmühlen… - PAIN®, 2011 - Elsevier
Quantitative sensory testing (QST) is an instrument to assess positive and negative sensory
signs, helping to identify mechanisms underlying pathologic pain conditions. In this study, …