User profiles for Garrit Koller

Garrit Koller

King's College London
Verified email at kcl.ac.uk
Cited by 1447

Collagen cross-linkers on dentin bonding: Stability of the adhesive interfaces, degree of conversion of the adhesive, cytotoxicity and in situ MMP inhibition

…, CG Moreira, VB Gotti, VP Feitosa, G Koller… - Dental Materials, 2016 - Elsevier
Objective To investigate the effect of collagen cross-links on the stability of adhesive properties,
the degree of conversion within the hybrid layer, cytotoxicity and the inhibition potential …

[HTML][HTML] ADAM8 as a drug target in pancreatic cancer

U Schlomann, G Koller, C Conrad, T Ferdous… - Nature …, 2015 - nature.com
Pancreatic ductal adenocarcinoma (PDAC) has a grim prognosis with <5% survivors after 5
years. High expression levels of ADAM8, a metalloprotease disintegrin, are correlated with …

Effects of MMP inhibitors incorporated within dental adhesives

A Almahdy, G Koller, S Sauro… - Journal of dental …, 2012 - journals.sagepub.com
Matrix metalloproteinase (MMP) inhibition has been shown to reduce adhesive bond
degradation when applied as a pre-conditioner, adding to clinical steps in the placement of …

Tumor necrosis factor-α (TNF-α) regulates shedding of TNF-α receptor 1 by the metalloprotease-disintegrin ADAM8: evidence for a protease-regulated feedback loop …

JW Bartsch, D Wildeboer, G Koller, S Naus… - Journal of …, 2010 - Soc Neuroscience
Tumor necrosis factor α (TNF-α) is a potent cytokine in neurodegenerative disorders, but its
precise role in particular brain disorders is ambiguous. In motor neuron (MN) disease of the …

Effects of bioactive glass and β‐TCP containing three‐dimensional laser sintered polyetheretherketone composites on osteoblasts in vitro

…, R Lutz, H Münstedt, G Koller… - … Research Part A: An …, 2008 - Wiley Online Library
Because of their excellent physical properties nonresorbable thermoplastic polymers have
become more important for the field of reconstructive surgery. Aim of the present study was to …

Assessing the diagnostic importance of nonviable bacterial cells in respiratory infections

GB Rogers, FA Stressmann, G Koller, T Daniels… - … and infectious disease, 2008 - Elsevier
Identification of bacteria in clinical samples is fundamental to combating infections. Modern
molecular genetic approaches exploit nucleic acids signals from clinical samples. However, …

The metalloprotease-disintegrin ADAM8 contributes to temozolomide chemoresistance and enhanced invasiveness of human glioblastoma cells

…, ML Biniossek, C Culmsee, H Strik, G Koller… - Neuro …, 2015 - academic.oup.com
Background Despite multimodal treatment, glioblastoma (GBM) therapy with temozolomide (TMZ)
remains inefficient due to chemoresistance. Matrix metalloproteinase (MMP) and a …

[HTML][HTML] Combined Systems Approaches Reveal Highly Plastic Responses to Antimicrobial Peptide Challenge in Escherichia coli

…, N Rehnnuma, SBTA Amos, G Koller… - PLoS …, 2014 - journals.plos.org
Obtaining an in-depth understanding of the arms races between peptides comprising the
innate immune response and bacterial pathogens is of fundamental interest and will inform the …

The pathway to intelligent implants: osteoblast response to nano silicon-doped hydroxyapatite patterning

G Munir, G Koller, L Di Silvio… - Journal of the …, 2011 - royalsocietypublishing.org
Bioactive hydroxyapatite (HA) with addition of silicon (Si) in the crystal structure (silicon-doped
hydroxyapatite (SiHA)) has become a highly attractive alternative to conventional HA in …

Characterization of root canal microbiota in teeth diagnosed with irreversible pulpitis

S Zahran, E Witherden, F Mannocci, G Koller - Journal of Endodontics, 2021 - Elsevier
Introduction Previous studies have shown that in teeth presenting with symptoms of irreversible
pulpitis (IP), bacteria and their by-products driving inflammation are confined mainly …