Excitatory synaptic transmission stimulates brain tissue glycolysis. This phenomenon is the
signal detected in FDG-PET imaging and, through enhanced lactate production, is also …

The Cl – channel ClC-2 is expressed in transporting epithelia and has been proposed as an
alternative route for Cl – efflux that might compensate for the malfunction of CFTR in cystic …

TASK-2 (KCNK5 or K 2P 5.1) is a background K + channel that is opened by extracellular
alkalinization and plays a role in renal bicarbonate reabsorption and central chemoreception. …

Activation of an apical Ca 2+ -activated Cl − channel (CaCC) triggers the secretion of saliva.
It was previously demonstrated that CaCC-mediated Cl − current and Cl − efflux are absent …

Ae4 (Slc4a9) belongs to the Slc4a family of Cl − /HCO 3 − exchangers and Na + -HCO 3 −
cotransporters, but its ion transport cycle is poorly understood. In this study, we find that native …

TASK-2 (K 2P 5.1) is a background K + channel opened by extra- or intracellular alkalinisation
that plays a role in renal bicarbonate handling, central chemoreception and cell volume …

Transcellular Cl − movement across acinar cells is the rate-limiting step for salivary gland
fluid secretion. Basolateral Nkcc1 Na + -K + -2Cl − cotransporters play a critical role in fluid …

In the last 15 years, remarkable progress has been realized in identifying the genes that
encode the ion-transporting proteins involved in exocrine gland function, including salivary …

We develop a mathematical model of a salivary gland acinar cell with the objective of
investigating the role of two $$\mathrm{Cl}^-/\mathrm{HCO}_3^-$$ Cl - / HCO 3 - exchangers from …

TASK-2 is a K 2P K + channel considered as a candidate to mediate CO 2 sensing in central
chemosensory neurons in mouse. Neuroepithelial cells in zebrafish gills sense CO 2 levels …