Prevalence of motor impairment in autism spectrum disorders

X Ming, M Brimacombe, GC Wagner - Brain and Development, 2007 - Elsevier
Autism spectrum disorders (ASD) are manifest as impairments in social interaction, language
and speech development, and the appearance of repetitive behaviors with restricted …

Long-lasting depletions of striatal dopamine and loss of dopamine uptake sites following repeated administration of methamphetamine

GC Wagner, GA Ricaurte, LS Seiden, CR Schuster… - Brain research, 1980 - Elsevier
Repeated administration of high doses of methamphetamine produced long-term decreases
in dopamine (DA) levels and in the number of DA uptake sites in the rat striatum. These two …

Autism spectrum disorders: concurrent clinical disorders

…, B Zimmerman-Bier, GC Wagner - Journal of child …, 2008 - journals.sagepub.com
Individuals with autism spectrum disorder are heterogeneous in clinical presentation,
concurrent disorders, and developmental outcomes. This study characterized the clinical co-…

A new neurobehavioral model of autism in mice: pre-and postnatal exposure to sodium valproate

GC Wagner, KR Reuhl, M Cheh, P McRae… - Journal of autism and …, 2006 - Springer
Autism symptoms, including impairments in language development, social interactions, and
motor skills, have been difficult to model in rodents. Since children exposed in utero to …

En2 knockout mice display neurobehavioral and neurochemical alterations relevant to autism spectrum disorder

…, X Ming, E Jacobsen, S Kamdar, GC Wagner - Brain research, 2006 - Elsevier
Autism spectrum disorder (ASD) is a prevalent and inheritable neurodevelopmental disorder.
Recent human genetic studies are consistent with the homeobox transcription factor, …

Use of clonidine in children with autism spectrum disorders

X Ming, E Gordon, N Kang, GC Wagner - Brain and Development, 2008 - Elsevier
Children with autism spectrum disorders (ASD) often exhibit sleep and behavioral disorders.
Treatment of sleep disorders can be difficult in these children. Clonidine, an α2-adrenergic …

Current research on methamphetamine-induced neurotoxicity: animal models of monoamine disruption

T Kita, GC Wagner, T Nakashima - Journal of pharmacological …, 2003 - jstage.jst.go.jp
Methamphetamine (METH)-induced neurotoxicity is characterized by a long-lasting depletion
of striatal dopamine (DA) and serotonin as well as damage to striatal dopaminergic and …

Gastrointestinal dysfunction in children with autism spectrum disorders

V Kang, GC Wagner, X Ming - Autism Research, 2014 - Wiley Online Library
Gastrointestinal ( GI ) dysfunctions are frequently reported by parents of children with autism
spectrum disorders ( ASD ) and have been recently recognized as a comorbid condition. …

Sleep insufficiency, sleep health problems and performance in high school students

…, S Buchman, CE Sarris, GC Wagner - Clinical Medicine …, 2011 - journals.sagepub.com
A survey on sleep schedule, sleep health, school performance and school start times was
conducted in 1,941 adolescents. A high level of early and circadian-disadvantaged sleep/…

VPA-induced apoptosis and behavioral deficits in neonatal mice

CL Yochum, P Dowling, KR Reuhl, GC Wagner, X Ming - Brain research, 2008 - Elsevier
Sodium valproate (VPA) administered to neonatal mice causes cognitive and motor deficits
similar to those observed in humans with autism. In an effort to further evaluate similarities …