User profiles for Gerardo Biella

Gerardo Biella

Department of Biology and Biotechnology, University of Pavia.
Verified email at unipv.it
Cited by 3957

[HTML][HTML] Niche-independent symmetrical self-renewal of a mammalian tissue stem cell

…, T Gorba, E Reitano, M Toselli, G Biella… - PLoS …, 2005 - journals.plos.org
Pluripotent mouse embryonic stem (ES) cells multiply in simple monoculture by symmetrical
divisions. In vivo, however, stem cells are generally thought to depend on specialised …

Long-term tripotent differentiation capacity of human neural stem (NS) cells in adherent culture

Y Sun, S Pollard, L Conti, M Toselli, G Biella… - Molecular and Cellular …, 2008 - Elsevier
Stem cell lines that provide a renewable and scaleable supply of central nervous system cell
types would constitute an invaluable resource for basic and applied neurobiology. Here we …

Developmentally coordinated extrinsic signals drive human pluripotent stem cell differentiation toward authentic DARPP-32+ medium-sized spiny neurons

…, G Martino, RA Barker, SB Dunnett, G Biella… - …, 2013 - journals.biologists.com
Medium-sized spiny neurons (MSNs) are the only neostriatum projection neurons, and their
degeneration underlies some of the clinical features of Huntington’s disease. Using …

Activity-dependent pH shifts and periodic recurrence of spontaneous interictal spikes in a model of focal epileptogenesis

M de Curtis, A Manfridi, G Biella - Journal of Neuroscience, 1998 - Soc Neuroscience
The mechanisms that control the periodicity of spontaneous epileptiform cortical potentials
were investigated in the in vitro isolated guinea pig brain preparation. A brief intracortical …

Olfactory inputs activate the medial entorhinal cortex via the hippocampus

G Biella, M de Curtis - Journal of neurophysiology, 2000 - journals.physiology.org
The lateral and medial regions of the entorhinal cortex differ substantially in terms of
connectivity and pattern of activation. With regard to olfactory input, a detailed and extensive …

Molecular and functional definition of the developing human striatum

…, M Toselli, C Farina, RA Barker, G Biella… - Nature …, 2014 - nature.com
The complexity of the human brain derives from the intricate interplay of molecular instructions
during development. Here we systematically investigated gene expression changes in the …

Transient oxytocin signaling primes the development and function of excitatory hippocampal neurons

…, MC Ambrozkiewicz, F Guzzi, M Gravati, G Biella… - Elife, 2017 - elifesciences.org
10.7554/eLife.22466.001 Beyond its role in parturition and lactation, oxytocin influences
higher brain processes that control social behavior of mammals, and perturbed oxytocin …

Human pluripotent stem cell differentiation into authentic striatal projection neurons

…, A Faedo, S Camnasio, M Toselli, G Biella… - Stem Cell Reviews and …, 2013 - Springer
Here we present the principles and steps of a protocol that we have recently developed for
the differentiation of hES/iPS cells into the authentic human striatal projection medium spiny …

Evidence for spatial modules mediated by temporal synchronization of carbachol-induced gamma rhythm in medial entorhinal cortex

CT Dickson, G Biella, M De Curtis - Journal of Neuroscience, 2000 - Soc Neuroscience
Fast (γ) oscillations in the cortex underlie the rapid temporal coordination of large-scale
neuronal assemblies in the processing of sensory stimuli. Cortical γ rhythm is modulated in vivo …

NMDA receptors elicit flux-independent intracellular Ca2+ signals via metabotropic glutamate receptors and flux-dependent nitric oxide release in human brain …

…, G Pellavio, P Spaiardi, L Botta, U Laforenza, G Biella… - Cell Calcium, 2021 - Elsevier
The excitatory neurotransmitter glutamate gates post-synaptic N-methyl-d-aspartate (NMDA)
receptors (NMDARs) to mediate extracellular Ca 2+ entry and stimulate neuronal nitric …