User profiles for Gerardo Biella
Gerardo BiellaDepartment of Biology and Biotechnology, University of Pavia. Verified email at unipv.it Cited by 3957 |
[HTML][HTML] Niche-independent symmetrical self-renewal of a mammalian tissue stem cell
Pluripotent mouse embryonic stem (ES) cells multiply in simple monoculture by symmetrical
divisions. In vivo, however, stem cells are generally thought to depend on specialised …
divisions. In vivo, however, stem cells are generally thought to depend on specialised …
Long-term tripotent differentiation capacity of human neural stem (NS) cells in adherent culture
Stem cell lines that provide a renewable and scaleable supply of central nervous system cell
types would constitute an invaluable resource for basic and applied neurobiology. Here we …
types would constitute an invaluable resource for basic and applied neurobiology. Here we …
Developmentally coordinated extrinsic signals drive human pluripotent stem cell differentiation toward authentic DARPP-32+ medium-sized spiny neurons
Medium-sized spiny neurons (MSNs) are the only neostriatum projection neurons, and their
degeneration underlies some of the clinical features of Huntington’s disease. Using …
degeneration underlies some of the clinical features of Huntington’s disease. Using …
Activity-dependent pH shifts and periodic recurrence of spontaneous interictal spikes in a model of focal epileptogenesis
M de Curtis, A Manfridi, G Biella - Journal of Neuroscience, 1998 - Soc Neuroscience
The mechanisms that control the periodicity of spontaneous epileptiform cortical potentials
were investigated in the in vitro isolated guinea pig brain preparation. A brief intracortical …
were investigated in the in vitro isolated guinea pig brain preparation. A brief intracortical …
Olfactory inputs activate the medial entorhinal cortex via the hippocampus
G Biella, M de Curtis - Journal of neurophysiology, 2000 - journals.physiology.org
The lateral and medial regions of the entorhinal cortex differ substantially in terms of
connectivity and pattern of activation. With regard to olfactory input, a detailed and extensive …
connectivity and pattern of activation. With regard to olfactory input, a detailed and extensive …
Molecular and functional definition of the developing human striatum
The complexity of the human brain derives from the intricate interplay of molecular instructions
during development. Here we systematically investigated gene expression changes in the …
during development. Here we systematically investigated gene expression changes in the …
Transient oxytocin signaling primes the development and function of excitatory hippocampal neurons
…, MC Ambrozkiewicz, F Guzzi, M Gravati, G Biella… - Elife, 2017 - elifesciences.org
10.7554/eLife.22466.001 Beyond its role in parturition and lactation, oxytocin influences
higher brain processes that control social behavior of mammals, and perturbed oxytocin …
higher brain processes that control social behavior of mammals, and perturbed oxytocin …
Human pluripotent stem cell differentiation into authentic striatal projection neurons
Here we present the principles and steps of a protocol that we have recently developed for
the differentiation of hES/iPS cells into the authentic human striatal projection medium spiny …
the differentiation of hES/iPS cells into the authentic human striatal projection medium spiny …
Evidence for spatial modules mediated by temporal synchronization of carbachol-induced gamma rhythm in medial entorhinal cortex
CT Dickson, G Biella, M De Curtis - Journal of Neuroscience, 2000 - Soc Neuroscience
Fast (γ) oscillations in the cortex underlie the rapid temporal coordination of large-scale
neuronal assemblies in the processing of sensory stimuli. Cortical γ rhythm is modulated in vivo …
neuronal assemblies in the processing of sensory stimuli. Cortical γ rhythm is modulated in vivo …
NMDA receptors elicit flux-independent intracellular Ca2+ signals via metabotropic glutamate receptors and flux-dependent nitric oxide release in human brain …
The excitatory neurotransmitter glutamate gates post-synaptic N-methyl-d-aspartate (NMDA)
receptors (NMDARs) to mediate extracellular Ca 2+ entry and stimulate neuronal nitric …
receptors (NMDARs) to mediate extracellular Ca 2+ entry and stimulate neuronal nitric …