In the inner ear, the auditory and vestibular systems detect and translate sensory information
regarding sound and balance. The sensory cells that transform mechanical input into an …

Mutations in myosin-VIIa (MYO7A) cause Usher syndrome type 1, characterized by combined
deafness and blindness. MYO7A is proposed to function as a motor that tensions the hair …

Hair cells detect sound and motion through a mechano-electric transduction (MET) process
mediated by tip links connecting shorter stereocilia to adjacent taller stereocilia. Adaptation …

Sound detection in auditory sensory hair cells depends on the deflection of the stereocilia
hair bundle which opens mechano-electric transduction (MET) channels. Adaptation is …

Hair cells of the auditory and vestibular systems transform mechanical input into electrical
potentials through the mechanoelectrical transduction process (MET). Deflection of the …

The purpose of this study was to analyze the physiological features of peripheral blood
mononuclear cells ( PBMCs ) isolated from healthy female trekkers before and after physical …

Hair cell mechanosensitivity resides in the sensory hair bundle, an apical protrusion of actin-filled
stereocilia arranged in a staircase pattern. Hair bundle deflection activates mechano-…

The presence of microgravity conditions deeply affects the human body functions at the
systemic, organ and cellular levels. This study aimed to investigate the effects induced by …

Neuronal growth-associated protein 43 (GAP43) has crucial roles in the nervous system,
and during development, regeneration after injury, and learning and memory. GAP43 is …

The “diseases of affluence” are defined as particular medical conditions determined by an
increasing wealth in a society and to the consequent increase in life expectancy and change …