The re-expression of hindlimb locomotion after complete spinal cord injuries (SCIs) is caused
by the presence of a spinal central pattern generator (CPG) for locomotion. After partial SCI…

Serotonin (5-hydroxytryptamine, 5-HT) is acknowledged as a major neuromodulator of nervous
systems in both invertebrates and vertebrates. It has been proposed for several decades …

The present paper reviews aspects of locomotor sensorimotor interactions by focussing on
work performed in spinal cats. We provide a brief overview of spinal locomotion and describe …

We have analysed the action of the neuromodulatory catecholamine, dopamine (DA), on
the lumbar locomotor network using an isolated in vitro newborn rat spinal cord preparation. …

L-3,4-dihydroxyphenylalanine (L-DOPA) has been successfully used in the treatment of
Parkinson’s disease (PD) for more than 50 years. It fulfilled the criteria to cross the blood–brain …

The basal ganglia (BG) inhibit movements through two independent circuits: the striatal
neuron-indirect and the subthalamic nucleus-hyperdirect pathways. These pathways exert …

The recovery of voluntary quadrupedal locomotion after an incomplete spinal cord injury
can involve different levels of the CNS, including the spinal locomotor circuitry. The latter …

Traumatic brain injury (TBI) is a leading cause of hospital visits in pediatric patients and often
leads to long‐term disorders even in cases of mild severity. White matter (WM) alterations …

Spinal cord injury (SCI) is one of the leading causes of neurological disability and death. So
far, there is no satisfactory treatment for SCI, because of its complex and ill-defined …

Large cholinergic synaptic terminals known as C-boutons densely innervate the soma and
proximal dendrites of motoneurons that are prone to neurodegeneration in amyotrophic …