Sister grouping of chimpanzees and humans as revealed by genome-wide phylogenetic analysis of brain gene expression profiles

…, RM Johnson, PR Hof, G Kapatos… - Proceedings of the …, 2004 - National Acad Sciences
Gene expression profiles from the anterior cingulate cortex (ACC) of human, chimpanzee,
gorilla, and macaque samples provide clues about genetic regulatory changes in human and …

Gene expression profile of the nucleus accumbens of human cocaine abusers: evidence for dysregulation of myelin

…, CJ Schmidt, DM Kuhn, G Kapatos… - Journal of …, 2004 - Wiley Online Library
Chronic cocaine abuse induces long‐term neural adaptations as a consequence of alterations
in gene expression. This study was undertaken to identify those transcripts differentially …

Mining Affymetrix microarray data for long non‐coding RNAs: altered expression in the nucleus accumbens of heroin abusers

…, L Lipovich, J Blythe, H Jia, G Kapatos… - Journal of …, 2011 - Wiley Online Library
J. Neurochem. (2011) 116, 459–466. Abstract Although recent data suggest that some long
non‐coding RNAs (lncRNAs) exert widespread effects on gene expression and organelle …

[HTML][HTML] Distinctive profiles of gene expression in the human nucleus accumbens associated with cocaine and heroin abuse

DN Albertson, CJ Schmidt, G Kapatos… - …, 2006 - nature.com
Drug abuse is thought to induce long-term cellular and behavioral adaptations as a result of
alterations in gene expression. Understanding the molecular consequences of addiction …

Layer-specific CREB target gene induction in human neocortical epilepsy

TL Beaumont, B Yao, A Shah, G Kapatos… - Journal of …, 2012 - Soc Neuroscience
Epilepsy is a disorder of recurrent seizures that affects 1% of the population. To understand
why some areas of cerebral cortex produce seizures and others do not, we identified …

Gene transfer of human guanosine 5′-triphosphate cyclohydrolase I restores vascular tetrahydrobiopterin level and endothelial function in low renin hypertension

…, KJ Lookingland, GD Fink, C Hesslinger, G Kapatos… - Circulation, 2003 - Am Heart Assoc
Background— We recently reported that arterial superoxide (O 2 − ) is augmented by increased
endothelin-1 (ET-1) in deoxycorticosterone acetate (DOCA)-salt hypertension, a model …

Dopamine transporter mRNA content in human substantia nigra decreases precipitously with age.

…, DJ Goebel, B Cassin, G Kapatos - Proceedings of the …, 1992 - National Acad Sciences
The dopamine transporter is the primary means of inactivating synaptic dopamine as well
as a major site of action for psychostimulants (such as cocaine and amphetamine) and for …

CREBH couples circadian clock with hepatic lipid metabolism

…, AC Liu, L Yin, JD Lin, PD Walker, G Kapatos… - Diabetes, 2016 - Am Diabetes Assoc
The circadian clock orchestrates diverse physiological processes critical for health and
disease. CREB, hepatocyte specific (CREBH) is a liver-enriched, endoplasmic reticulum (ER)–…

Functional association of the parkin gene promoter with idiopathic Parkinson's disease

…, PJ Lockhart, KM Wilkes, G Kapatos… - Human molecular …, 2002 - academic.oup.com
Loss-of-function mutations in the parkin gene were first identified in autosomal recessive
juvenile parkinsonism (AR-JP). Subsequently, parkin mutations were found in many early-onset …

Paraventricular area: critical focus of a longitudinal neurocircuitry mediating food intake

RM Gold, AP Jones, PE Sawchenko, G Kapatos - Physiology & behavior, 1977 - Elsevier
KAPATOS. Paraventricular area: critical focus of a longitudinal … Kapatos. Delayed hyperphagia
and increased body length … Kapatos and RJ Carey. A retracting wire knife for stereotaxic …