32 JOVE & HANAFUSA the rapid and dramatic cellular response. Remarkable progress has
been made during the past decade in understanding the origin, structure, and function of …

Src homology 2 (SH2) domains provide specificity to intracellular signaling by binding to
specific phosphotyrosine (phospho-Tyr)-containing sequences. We recently developed a …

The discovery that Src homology 2 (SH2) domains provide phosphorylation-dependent and
sequence-specific contacts for assembly of receptor signaling complexes has provided a …

The Src homology domains SH2 and SH3 are modular components present in many signal
transduction proteins. They allow rapid formation of stable protein complexes and may also …

The singularity problem is an inherent problem in controlling robot manipulators with articulated
configuration. In this paper, we propose to determine the joint motion for the requested …

In this paper, we describe a new scheme for redundancy control of robot manipulators. We
introduce the concept of task priority in relation to the inverse kinematic problem of redundant …

… Cells were labelled for 4 h with 1 mCi ["H]leucine (60 Ci mmol"; Amersham) in 1 ml.
Kinase assays were performed in 50 mM HEPES (pH 7.4), 10 mM MnCl, , 10 Ci [y.*P]ATP (3,000 …

… After induction with 0.5 mM IPTG for 3 h, cells were harvested by centrifugation and
resuspended in 100 ml of 20 mM HEPES, pH75, 10 mM EDTA, 5 mM DTT, 5 g ml" of leupeptin (…

Axl, Sky, and Mer, members of an Axl/Sky receptor tyrosine kinase subfamily, are typified by
the cell adhesion molecule-related extracellular domain. The product of growth arrest-…

… But the activation of SAPK/JNK by TGF-β is maximal 12 h after stimulation, whereas TGF-β
induces the activation of TAK1 within 15 min. These results seemed to imply that TAK1 is not …