[HTML][HTML] Intermittent hypoxia attenuates ischemia/reperfusion induced apoptosis in cardiac myocytes via regulating Bcl-2/Bax expression
JW Dong, HF Zhu, WZ Zhu, HL Ding, TM Ma, ZN Zhou - Cell research, 2003 - nature.com
Intermittent hypoxia has been shown to provide myocardial protection against ishemia/reperfusion-induced
injury. Cardiac myocyte loss through apoptosis has been reported in …
injury. Cardiac myocyte loss through apoptosis has been reported in …
Brain-derived neurotrophic factor in the mesolimbic reward circuitry mediates nociception in chronic neuropathic pain
…, MJ Liu, H Liu, S Zhang, XY Guo, JX Yang, HL Ding… - Biological …, 2017 - Elsevier
Background The mesolimbic reward system plays a critical role in modulating nociception;
however, its underlying molecular, cellular, and neural circuitry mechanisms remain unknown…
however, its underlying molecular, cellular, and neural circuitry mechanisms remain unknown…
Disinhibition of mesolimbic dopamine circuit by the lateral hypothalamus regulates pain sensation
…, T Fang, JX Yang, L Song, H Liu, HL Ding… - Journal of …, 2023 - Soc Neuroscience
Our recent study demonstrated the critical role of the mesolimbic dopamine (DA) circuit and
its brain-derived neurotropic factor (BDNF) signaling in mediating neuropathic pain. The …
its brain-derived neurotropic factor (BDNF) signaling in mediating neuropathic pain. The …
Caveolin-1 in the anterior cingulate cortex modulates chronic neuropathic pain via regulation of NMDA receptor 2B subunit
…, LY Hao, L Yu, P Wu, CJ Shao, HL Ding… - Journal of …, 2015 - Soc Neuroscience
Chronic pain is still a basic science and clinical challenge. Unraveling of the neurobiological
mechanisms involved in chronic pain will offer novel targets for the development of …
mechanisms involved in chronic pain will offer novel targets for the development of …
Hydroxymethylation of microRNA-365-3p regulates nociceptive behaviors via Kcnh2
…, GF Li, LY Hao, LJ Zhu, YQ Li, HL Ding… - Journal of …, 2016 - Soc Neuroscience
DNA 5-hydroxylmethylcytosine (5hmC) catalyzed by ten-eleven translocation methylcytosine
dioxygenase (TET) occurs abundantly in neurons of mammals. However, the in vivo causal …
dioxygenase (TET) occurs abundantly in neurons of mammals. However, the in vivo causal …
Inducible nitric oxide synthase contributes to intermittent hypoxia against ischemia/reperfusion injury
H Ding, H Zhu, J Dong, W Zhu, W Yang… - Acta Pharmacologica …, 2005 - nature.com
Aim: To investigate the role of inducible nitric oxide synthase (iNOS)-derived nitric oxide (NO)
in the cardioprotection of intermittent hypoxia (IH) against ischemia/reperfusion (I/R) injury. …
in the cardioprotection of intermittent hypoxia (IH) against ischemia/reperfusion (I/R) injury. …
GABAergic neurons in the dorsal–intermediate lateral septum regulate sleep–wakefulness and anesthesia in mice
…, XX Kong, YM Yu, JX Yang, H Zhang, HL Ding… - …, 2021 - pubs.asahq.org
Background The γ-aminobutyric acid–mediated (GABAergic) inhibitory system in the brain
is critical for regulation of sleep–wake and general anesthesia. The lateral septum contains …
is critical for regulation of sleep–wake and general anesthesia. The lateral septum contains …
Brain-derived neurotrophic factor–mediated projection-specific regulation of depressive-like and nociceptive behaviors in the mesolimbic reward circuitry
…, H Liu, YM Zhang, SY Wu, Y Song, B Juarez, HL Ding… - Pain, 2018 - journals.lww.com
Increasing evidence suggests that the mesolimbic reward system plays critical roles in the
regulation of depression and nociception; however, its circuitry and cellular mechanisms …
regulation of depression and nociception; however, its circuitry and cellular mechanisms …
Activation of the spinal ERK signaling pathway contributes naloxone-precipitated withdrawal in morphine-dependent rats
JL Cao, JH He, HL Ding, YM Zeng - Pain, 2005 - Elsevier
Extracellular signal-regulated kinase (ERK), a mitogen-activated protein kinases (MAPK),
transduces a broad range of extracellular stimuli into diverse intracellular responses. Recent …
transduces a broad range of extracellular stimuli into diverse intracellular responses. Recent …
Contralateral projection of anterior cingulate cortex contributes to mirror-image pain
…, WN Zhao, QZ Li, JX Yang, S An, HL Ding… - Journal of …, 2021 - Soc Neuroscience
Long-term limb nerve injury often leads to mirror-image pain (MIP), an abnormal pain sensation
in the limb contralateral to the injury. Although it is clear that MIP is mediated in part by …
in the limb contralateral to the injury. Although it is clear that MIP is mediated in part by …