Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

…, IR Mackenzie, H Feldman, W Feiden, HA Kretzschmar… - Science, 2006 - science.org
Ubiquitin-positive, tau- and α-synuclein–negative inclusions are hallmarks of frontotemporal
lobar degeneration with ubiquitin-positive inclusions and amyotrophic lateral sclerosis. …

Pathological TDP‐43 distinguishes sporadic amyotrophic lateral sclerosis from amyotrophic lateral sclerosis with SOD1 mutations

…, A Eisen, L McClusky, HA Kretzschmar… - Annals of Neurology …, 2007 - Wiley Online Library
Objective Amyotrophic lateral sclerosis (ALS) is a common, fatal motor neuron disorder with
no effective treatment. Approximately 10% of cases are familial ALS (FALS), and the most …

IAPWS industrial formulation 1997 for the thermodynamic properties of water and steam

W Wagner, HJ Kretzschmar - … steam tables: properties of water and steam …, 2008 - Springer
At the IAPWS meeting in Erlangen, Germany in 1997, the “IAPWS Industrial Formulation
1997 for the Thermodynamic Properties of Water and Steam” was adopted as the new …

The C9orf72 GGGGCC Repeat Is Translated into Aggregating Dipeptide-Repeat Proteins in FTLD/ALS

…, K Rentzsch, E Kremmer, B Schmid, HA Kretzschmar… - Science, 2013 - science.org
Expansion of a GGGGCC hexanucleotide repeat upstream of the C9orf72 coding region is the
most common cause of familial frontotemporal lobar degeneration and amyotrophic lateral …

[BOOK][B] International Steam Tables-Properties of Water and Steam based on the Industrial Formulation IAPWS-IF97: Tables, Algorithms, Diagrams, and CD-ROM …

W Wagner, HJ Kretzschmar - 2007 - books.google.com
Steam tables for practical industrial use are presented which have been calculated using
the international standard for the thermodynamic properties of water and steam, the IAPWS-…

Synapse formation and function is modulated by the amyloid precursor protein

…, G Mitteregger, B Krebs, HA Kretzschmar… - Journal of …, 2006 - Soc Neuroscience
The amyloid precursor protein (APP) is critical in the pathogenesis of Alzheimer's disease.
The question of its normal biological function in neurons, in which it is predominantly located …

A new subtype of frontotemporal lobar degeneration with FUS pathology

…, R Rademakers, S Roeber, M Baker, HA Kretzschmar… - Brain, 2009 - academic.oup.com
Frontotemporal dementia (FTD) is a clinical syndrome with a heterogeneous molecular
basis. The neuropathology associated with most FTD is characterized by abnormal cellular …

Subcellular localization of wild-type and Parkinson's disease-associated mutant α-synuclein in human and transgenic mouse brain

…, A Probst, E Kremmer, HA Kretzschmar… - Journal of …, 2000 - Soc Neuroscience
Mutations in the α-synuclein (αSYN) gene are associated with rare cases of familial Parkinson's
disease, and αSYN is a major component of Lewy bodies and Lewy neurites. Here we …

Prion protein-deficient cells show altered response to oxidative stress due to decreased SOD-1 activity

…, WJ Schulz-Schaeffer, B Schmidt, HA Kretzschmar - Experimental …, 1997 - Elsevier
The cellular function of the prion protein (PrP C ), a cell surface glycoprotein expressed in
neurones and astrocytes, has not been elucidated. Cell culture experiments reveal that …

Role of microglia and host prion protein in neurotoxicity of a prion protein fragment

DR Brown, B Schmidt, HA Kretzschmar - Nature, 1996 - nature.com
THE prion protein PrP c is a glycoprotein of unknown function 1 normally found in neurons 2
and glia 3 . It is involved in diseases such as bovine spongiform encephalopathy (BSE), …